| Group | Procedure | Rating | Comments | RRL* |
| | External beam radiation therapy alone (EBRT) | 9 | | |
| | EBRT with androgen ablation | 3 | If more than 50% cores positive or high volume disease, then hormone therapy may be appropriate. | |
| External Beam Pelvic Nodes Dose | 4500 cGy/25 fractions | 2 | If more than 50% cores positive or high volume disease, may consider treating pelvic nodes. | |
| External Beam Pelvic Nodes Dose | 5040 cGy/28 fractions | 2 | If more than 50% cores positive or high volume disease, may consider treating pelvic nodes. | |
| Prostate Dose (max. includes pelvic dose) | 8100 cGy/45 fractions | 7 | | |
| Prostate Dose (max. includes pelvic dose) | 7800 cGy/42 fractions | 8 | | |
| Prostate Dose (max. includes pelvic dose) | 7560 cGy/42 fractions | 7 | | |
| Prostate Dose (max. includes pelvic dose) | 7020 cGy/39 fractions | 5 | | |
| Prostate Dose (max. includes pelvic dose) | 6660 cGy/37 fractions | 2 | | |
| Prostate Dose (max. includes pelvic dose) | < or = 5940 cGy/33 fractions | 1 | | |
| External Beam Treatment Plan | IMRT | 8 | See the ACR Appropriateness Criteria® for External Beam Radiation Therapy Treatment Planning for Clinically Localized Prostate Cancer. | |
| External Beam Treatment Plan | Proton beam | 8 | See the ACR Appropriateness Criteria® for External Beam Radiation Therapy Treatment Planning for Clinically Localized Prostate Cancer. | |
| External Beam Treatment Plan | 3D-CT based plan | 7 | See the ACR Appropriateness Criteria® for External Beam Radiation Therapy Treatment Planning for Clinically Localized Prostate Cancer. | |
| External Beam Treatment Plan | 2D-CT based plan | 3 | See the ACR Appropriateness Criteria® for External Beam Radiation Therapy Treatment Planning for Clinically Localized Prostate Cancer. | |
| External Beam Treatment Plan | Non-CT based computerized plan | 2 | See the ACR Appropriateness Criteria® for External Beam Radiation Therapy Treatment Planning for Clinically Localized Prostate Cancer. | |
| Brachytherapy | LDR (permanent seeds) alone | 9 | See the ACR Appropriateness Criteria® for Permanent Source Brachytherapy for Prostate Cancer. | |
| Brachytherapy | EBRT with LDR brachytherapy boost | 3 | See the ACR Appropriateness Criteria® for Permanent Source Brachytherapy for Prostate Cancer. | |
| Brachytherapy | HDR (temporary implant) alone | 6 | See the ACR Appropriateness Criteria® for Permanent Source Brachytherapy for Prostate Cancer. | |
| Brachytherapy | EBRT with HDR boost | 3 | See the ACR Appropriateness Criteria® for Permanent Source Brachytherapy for Prostate Cancer. | |
| Nonradiation Therapy Alternatives | Radical prostatectomy (nerve sparing) | 9 | | |
| Nonradiation Therapy Alternatives | Cryoablation | 3 | | |
| Nonradiation Therapy Alternatives | Transurethral resection | 2 | | |
| Nonradiation Therapy Alternatives | Orchiectomy | 1 | | |