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*Relative Radiation Level
Procedure List
Topic:Definitive External Beam Irradiation in Stage T1 and T2 Prostate Cancer
Variant:63-year-old male, minimal dysuria and urinary frequency, in PSA screening program. PSA a year ago was 3.2, recent PSA 8.2 ng/ml. Rectal exam showed no palpable abnormality in the prostate. Multiple quadrant biopsies demonstrate adenocarcinoma. Gleason score 3+2=5. Metastatic workup negative.

GroupProcedureRatingCommentsRRL*
 External beam radiation therapy alone (EBRT) 9  
 EBRT with androgen ablation 3If more than 50% cores positive or high volume disease, then hormone therapy may be appropriate. 
External Beam Pelvic Nodes Dose4500 cGy/25 fractions2If more than 50% cores positive or high volume disease, may consider treating pelvic nodes. 
External Beam Pelvic Nodes Dose5040 cGy/28 fractions2If more than 50% cores positive or high volume disease, may consider treating pelvic nodes. 
Prostate Dose (max. includes pelvic dose)8100 cGy/45 fractions7  
Prostate Dose (max. includes pelvic dose)7800 cGy/42 fractions8  
Prostate Dose (max. includes pelvic dose)7560 cGy/42 fractions7  
Prostate Dose (max. includes pelvic dose)7020 cGy/39 fractions5  
Prostate Dose (max. includes pelvic dose)6660 cGy/37 fractions2  
Prostate Dose (max. includes pelvic dose)< or = 5940 cGy/33 fractions1  
External Beam Treatment PlanIMRT8See the ACR Appropriateness Criteria® for External Beam Radiation Therapy Treatment Planning for Clinically Localized Prostate Cancer. 
External Beam Treatment PlanProton beam8See the ACR Appropriateness Criteria® for External Beam Radiation Therapy Treatment Planning for Clinically Localized Prostate Cancer. 
External Beam Treatment Plan3D-CT based plan7See the ACR Appropriateness Criteria® for External Beam Radiation Therapy Treatment Planning for Clinically Localized Prostate Cancer. 
External Beam Treatment Plan2D-CT based plan3See the ACR Appropriateness Criteria® for External Beam Radiation Therapy Treatment Planning for Clinically Localized Prostate Cancer. 
External Beam Treatment PlanNon-CT based computerized plan2See the ACR Appropriateness Criteria® for External Beam Radiation Therapy Treatment Planning for Clinically Localized Prostate Cancer. 
BrachytherapyLDR (permanent seeds) alone9See the ACR Appropriateness Criteria® for Permanent Source Brachytherapy for Prostate Cancer. 
BrachytherapyEBRT with LDR brachytherapy boost3See the ACR Appropriateness Criteria® for Permanent Source Brachytherapy for Prostate Cancer. 
BrachytherapyHDR (temporary implant) alone6See the ACR Appropriateness Criteria® for Permanent Source Brachytherapy for Prostate Cancer. 
BrachytherapyEBRT with HDR boost3See the ACR Appropriateness Criteria® for Permanent Source Brachytherapy for Prostate Cancer. 
Nonradiation Therapy AlternativesRadical prostatectomy (nerve sparing)9  
Nonradiation Therapy AlternativesCryoablation3  
Nonradiation Therapy AlternativesTransurethral resection2  
Nonradiation Therapy AlternativesOrchiectomy1  

Appropriateness Criteria Scale

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1=Least appropriate                                           9=Most appropriate
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