Variant 1: Child. Traumatic visual loss. Suspected orbital injury. Initial imaging.
Variant 2: Child. Nontraumatic acute vision loss without papilledema. Initial imaging.
Variant 3: Child with isolated nystagmus. Initial imaging.
Variant 4: Child. Congenital or developmental abnormality leading to decreased visual acuity or vision loss. No leukocoria. Unilateral or bilateral. Initial imaging.
Variant 5: Child. Vision loss and suspected optic pathway tumor, with or without a history of neurofibromatosis type 1. Initial imaging.
Variant 6: Child. Six months of age or older. Papilledema detected on the ophthalmologic examination or signs of raised intracranial pressure. Initial imaging.
Variant 7: Child. Suspected orbital or periorbital infection. Initial imaging.
Variant 8: Child. Leukocoria or suspected intraocular mass. Initial imaging.
Appendix Key

A more complete discussion of the items presented below can be found by accessing the supporting documents at the designated hyperlinks.

Appropriateness Category:The panel’s recommendation for a procedure based on the assessment of the risks and benefits of performing the procedure for the specified clinical scenario.

SOE: Strength of Evidence. The assessment of the amount and quality of evidence found in the peer reviewed medical literature for an appropriateness recommendation.

  • References: The citation number and PMID for the reference(s) associated with the recommendation.
  • Study Quality: The assessment of the quality of an individual reference based on the number of study quality elements described in the reference.

RRL: Relative Radiation Level. A population based assessment of the amount of radiation a typical patient may be exposed to during the specified procedure.

Rating: The final rating (1-9 scale) for the procedure as determined by the panel during rating rounds.

Median: The median rating (1-9 scale) for the procedure as determined by the panel during rating rounds.

Final tabulations: A histogram showing the number of panel members who rated the procedure as noted in the column heading (ie, 1, 2, 3, etc.).

Additional supporting documents about the AC methodology and processes can be found at