Variant 1: 22-year-old man with stage IIA supradiaphragmatic Hodgkin lymphoma (ESR 8), treated with ABVD × 4 (PET/CT after 2 cycles) followed by involved-field radiotherapy (IFRT), now 1 month after treatment.
Variant 2: 28-year-old woman with stage IIBX supradiaphragmatic Hodgkin lymphoma (ESR 30), treated with ABVD × 6 (residual PET avidity after 2 cycles of ABVD, avidity resolved after 6 cycles of ABVD) followed by IFRT, now 1 month after treatment.
Variant 3: 68-year-old man with stage IA Hodgkin lymphoma with right cervical involvement (ESR 12), treated with ABVD × 4 (PET/CT after 4 cycles) followed by IFRT, now 1 month after treatment.
Variant 4: 32-year-old woman with history of stage IIA Hodgkin lymphoma with left neck and mediastinal involvement, treated with ABVD × 4 followed by IFRT completing treatment 5 years ago.
Variant 5: 40-year-old man with stage IIIB NS Hodgkin lymphoma involving right neck, mediastinum and para-aortic lymph nodes and ESR of 15 who achieved complete response to ABVD × 6 without radiation therapy per PET/CT, now 3 months after treatment.
Appendix Key

A more complete discussion of the items presented below can be found by accessing the supporting documents at the designated hyperlinks.

Appropriateness Category:The panel’s recommendation for a procedure based on the assessment of the risks and benefits of performing the procedure for the specified clinical scenario.

SOE: Strength of Evidence. The assessment of the amount and quality of evidence found in the peer reviewed medical literature for an appropriateness recommendation.

  • References: The citation number and PMID for the reference(s) associated with the recommendation.
  • Study Quality: The assessment of the quality of an individual reference based on the number of study quality elements described in the reference.

RRL: Relative Radiation Level. A population based assessment of the amount of radiation a typical patient may be exposed to during the specified procedure.

Rating: The final rating (1-9 scale) for the procedure as determined by the panel during rating rounds.

Median: The median rating (1-9 scale) for the procedure as determined by the panel during rating rounds.

Final tabulations: A histogram showing the number of panel members who rated the procedure as noted in the column heading (ie, 1, 2, 3, etc.).

Additional supporting documents about the AC methodology and processes can be found at www.acr.org/ac.