| 1. Batlle JC, Kirsch J, Bolen MA, et al. ACR Appropriateness Criteria® Chest Pain-Possible Acute Coronary Syndrome. J Am Coll Radiol 2020;17:S55-S69. |
Review/Other-Dx |
N/A |
Evidence-based guidelines to assist referring physicians and other providers in making the most appropriate imaging or treatment decision for chest pain-possible acute coronary syndrome. |
No results stated in abstract. |
4 |
| 2. American College of Radiology. ACR Appropriateness Criteria®: Nonischemic Myocardial Disease with Clinical Manifestations (Ischemic Cardiomyopathy Already Excluded). Available at: https://acsearch.acr.org/docs/3082580/Narrative/. |
Review/Other-Dx |
N/A |
Evidence-based guidelines to assist referring physicians and other providers in making the most appropriate imaging or treatment decision for a specific clinical condition. |
No abstract available. |
4 |
| 3. American College of Radiology. ACR Appropriateness Criteria®: Suspected Pulmonary Embolism. Available at: https://acsearch.acr.org/docs/69404/Narrative/. |
Review/Other-Dx |
N/A |
Evidence-based guidelines to assist referring physicians and other providers in making the most appropriate imaging or treatment decision for a specific clinical condition. |
No abstract available. |
4 |
| 4. American College of Radiology. ACR Appropriateness Criteria®: Acute Chest Pain-Suspected Aortic Dissection. Available at: https://acsearch.acr.org/docs/69402/Narrative/. |
Review/Other-Dx |
N/A |
Evidence-based guidelines to assist referring physicians and other providers in making the most appropriate imaging or treatment decision for a specific clinical condition. |
No abstract available. |
4 |
| 5. Reis SP, Majdalany BS, AbuRahma AF, et al. ACR Appropriateness Criteria® Pulsatile Abdominal Mass Suspected Abdominal Aortic Aneurysm. J Am Coll Radiol 2017;14:S258-S65. |
Review/Other-Dx |
N/A |
Evidence-based guidelines to assist referring physicians and other providers in making the most appropriate imaging or treatment decision for pulsatile abdominal mass suspected abdominal aortic aneurysm. |
No results stated in abstract. |
4 |
| 6. Francois CJ, Skulborstad EP, Majdalany BS, et al. ACR Appropriateness Criteria® Abdominal Aortic Aneurysm: Interventional Planning and Follow-Up. J Am Coll Radiol 2018;15:S2-S12. |
Review/Other-Dx |
N/A |
Evidence-based guidelines to assist referring physicians and other providers in making the most appropriate imaging or treatment decision for abdominal Aortic aneurysm: interventional planning and follow-up. |
No results stated in abstract. |
4 |
| 7. Cooper K, Majdalany BS, Kalva SP, et al. ACR Appropriateness Criteria® Lower Extremity Arterial Revascularization-Post-Therapy Imaging. J Am Coll Radiol 2018;15:S104-S15. |
Review/Other-Dx |
N/A |
Evidence-based guidelines to assist referring physicians and other providers in making the most appropriate imaging or treatment decision for lower extremity arterial revascularization-post-therapy imaging. |
No results stated in abstract. |
4 |
| 8. Expert Panel on Vascular Imaging:, Ahmed O, Hanley M, et al. ACR Appropriateness Criteria R Vascular Claudication-Assessment for Revascularization. [Review]. J. Am. Coll. Radiol.. 14(5S):S372-S379, 2017 May. |
Review/Other-Dx |
N/A |
Evidence-based guidelines to assist referring physicians and other providers in making the most appropriate imaging or treatment decision for vascular claudication, assessment for revascularization. |
No results stated in abstract. |
4 |
| 9. American College of Radiology. ACR–NASCI–SIR–SPR Practice Parameter for the Performance and Interpretation of Body Computed Tomography Angiography (CTA). Available at: https://www.acr.org/-/media/ACR/Files/Practice-Parameters/body-cta.pdf. |
Review/Other-Dx |
N/A |
Guidance document to promote the safe and effective use of diagnostic and therapeutic radiology by describing specific training, skills and techniques. |
No abstract available. |
4 |
| 10. Dijkema EJ, Leiner T, Grotenhuis HB. Diagnosis, imaging and clinical management of aortic coarctation. [Review]. Heart. 103(15):1148-1155, 2017 08. |
Review/Other-Dx |
N/A |
To provide an overview of the current state-of-the-art clinical diagnosis, diagnostic imaging algorithms, treatment and follow-up of patients with coarctation of the aorta (CoA). |
No results stated in abstract. |
4 |
| 11. Becker C, Soppa C, Fink U, et al. Spiral CT angiography and 3D reconstruction in patients with aortic coarctation. Eur Radiol. 7(9):1473-7, 1997. |
Review/Other-Dx |
18 patients |
To assess the reliability of spiral CT angiography (CTA) and 3D reconstruction in patients with aortic coarctation (CoA). |
Diameters derived from cardiac catheterization were compared with those from CTA in 8 patients. The degree of aortic stenosis was correlated with blood pressure gradients (BPG) in 12 patients. The difference between the diameters of the CoA and the pre- and poststenotic aorta derived from MIP and angiography was not statistically significant (p = 0.69). With SSD the internal thoracic artery was detected in 16 and the posterior intercostal artery in 13 cases. The degree of aortic stenosis correlated poorly with the BPG (r = 0.51, r2 = 0.26). |
4 |
| 12. Di Sessa TG, Di Sessa P, Gregory B, Vranicar M. The use of 3D contrast-enhanced CT reconstructions to project images of vascular rings and coarctation of the aorta. Echocardiography. 26(1):76-81, 2009 Jan. |
Observational-Dx |
13 patients |
To report our experience with the use of 3D reconstruction of contrast-enhanced CT scans using a simple, commercially available software program in evaluating coarctation of the aorta and vascular rings. |
Adequate CT scans and 3D reconstructions were obtained in 12 of 13 patients. There were 85-1,044 slices obtained in the adequate studies. We could not reconstruct a 3D image from a patient's CT scan that had only 22 slices. The anatomy defined by 3D was compared to 2D CT imaging and confirmed by cardiac catheterization or direct visualization in the operating room in the 12 patients with adequate 3D reconstructions. In 5 of 12 patients, 3D reconstructions provided valuable spatial information not observed in the conventional 2D scans. |
3 |
| 13. Hu XH, Huang GY, Pa M, et al. Multidetector CT angiography and 3D reconstruction in young children with coarctation of the aorta. Pediatr Cardiol. 29(4):726-31, 2008 Jul. |
Observational-Dx |
16 patients |
To assess the reliability of multidetector CT (MDCT) angiography and three-dimensional (3D) reconstruction in patients with coarctation of the aorta. |
Sixteen cases were diagnosed as coarctation of the aorta by MDCT. This included hypoplasia of the aortic arch (n = 5). The results were confirmed at the time of surgery. Diagnosis sensitivities of coarctation were 87.5% for axial and 100% for both multiplanar and 3D volume-rendered images. Moreover, MDCT was able to clearly display the location and extent of the coarctation. Focal defects were observed in 14 cases, and diffuse defects in 2 cases. The sensitivity of MDCT diagnosis for coarctation of the aorta was 100%, which was higher than that of CDE (87.5%). Ventricular septum defect was diagnosed by MDCT in 11 cases, with 1 missed, and the sensitivity was 91.7% (11/12), which was lower than that of CDE (100%; 12/12). In addition, six patients had patent ductus arteriosus. Two patients in this study had collateral vessel formation. |
4 |
| 14. Lee EY, Siegel MJ, Hildebolt CF, Gutierrez FR, Bhalla S, Fallah JH. MDCT evaluation of thoracic aortic anomalies in pediatric patients and young adults: comparison of axial, multiplanar, and 3D images. AJR Am J Roentgenol. 182(3):777-84, 2004 Mar. |
Observational-Dx |
14 patients |
To compare accuracies of axial, multiplanar, and 3D volume-rendered images in the diagnosis of thoracic aortic anomalies in pediatric patients and young adults. |
Average accuracies (average of the three observers for a correct diagnosis) were greater than or equal to 96% for diagnoses of aortic position and airway narrowing on all image types. For the diagnosis of coarctation, average sensitivities (average of the three observers for a true diagnosis) were 73% for axial, 100% for multiplanar, and 100% for 3D volume-rendered images. For the diagnosis of patent ductus arteriosus, average sensitivities were 78% for axial, 94% for multiplanar, and 89% for 3D volume-rendered images. No patients in this study had collateral vessel formation. For the diagnosis of absence of collateral vessel formation, average sensitivities were 100% for axial, 100% for multiplanar, and 100% for 3D volume-rendered images. There were no significant statistical differences in diagnostic performances, agreement with truth, or confidence scores among observers or imaging formats (p > 0.05). |
3 |
| 15. Mirzaee H, Henn T, Krause MJ, et al. MRI-based computational hemodynamics in patients with aortic coarctation using the lattice Boltzmann methods: Clinical validation study. J Magn Reson Imaging. 45(1):139-146, 2017 01. |
Review/Other-Dx |
12 patients |
To introduce a scheme based on a recent technique in computational hemodynamics, known as the lattice Boltzmann methods (LBM), to noninvasively measure pressure gradients in patients with a coarctation of the aorta (CoA). To provide evidence on the accuracy of the proposed scheme, the computed pressure drop values are compared against those obtained using the reference standard method of catheterization. |
There is a significant linear correlation between the pretreatment catheter pressure drops and those computed based on the LBM simulation, r=.85, P<.001. The bias was -0.58±4.1 mmHg and was not significant ( P=0.64) with a 95% confidence interval (CI) of -3.22 to 2.06. For the posttreatment results, the bias was larger and at -2.54±3.53 mmHg with a 95% CI of -0.17 to -4.91 mmHg. |
4 |
| 16. Nie P, Wang X, Cheng Z, et al. The value of low-dose prospective ECG-gated dual-source CT angiography in the diagnosis of coarctation of the aorta in infants and children. Clin Radiol. 67(8):738-45, 2012 Aug. |
Observational-Dx |
17 patients |
To investigate the value of prospective electrocardiogram (ECG)-gated dual-source computed tomography (DSCT) in the diagnosis of coarctation of the aorta (CoA). |
CoA was diagnosed in 17 patients by DSCT angiography and in 16 patients by TTE. A total of 46 separate cardiovascular abnormalities were confirmed by surgical findings. The diagnostic accuracy of DSCT angiography and TTE was 96.32% and 97.06%, respectively. There was no significant difference in the diagnostic accuracy between DSCT angiography and TTE (?(2) = 0, p > 0.05). The mean score of image quality was 4.2 ± 0.8. The mean effective dose was 0.69 ± 0.09 mSv. |
2 |
| 17. Nielsen JC, Powell AJ, Gauvreau K, Marcus EN, Prakash A, Geva T. Magnetic resonance imaging predictors of coarctation severity. Circulation. 111(5):622-8, 2005 Feb 08. |
Observational-Dx |
31 subjects |
To evaluate the ability of MRI to distinguish between mild versus moderate and severe coarctation (CoA) as determined by cardiac catheterization. |
Patients were divided into 2 groups on the basis of peak coarctation gradient by catheterization: <20 mm Hg (n=12) and > or =20 mm Hg (n=19). Patients with cardiac index <2.2 L x min(-1) x m(-2) by catheterization were excluded. By logistic regression analysis, the following variables simultaneously predicted coarctation gradient > or =20 mm Hg: (1) smallest aortic cross-sectional area (adjusted for body surface area) measured by planimetry from gadolinium-enhanced 3D magnetic resonance angiography (OR 1.71 for 10 mm2/m2 decrease, P=0.005) and (2) heart rate-corrected mean flow deceleration in the descending aorta measured by phase-velocity cine MRI (OR 1.68 for 100 mL/s(1.5) increase, P=0.018). For the combination of these variables, a predicted probability >0.38 had 95% sensitivity, 82% specificity, 90% positive and negative predictive values, and an area under the receiver-operator characteristics curve of 0.938. In a subsequent validation study, the prediction model correctly classified 9 of 10 patients, with no false-negatives. |
3 |
| 18. Peng L, Yang Z, Yu J, Chu Z, Chen D, Luo Y. [Clinical value of ECG-gated dual-source computed tomography and angiography in assessing coarctation of aorta]. [Chinese]. Shengwu Yixue Gongchengxue Zazhi/Journal of Biomedical Engineering. 30(1):89-94, 2013 Feb. |
Observational-Dx |
23 patients |
To explore the clinical value of ECG-gated dual-source CT angiography (DSCTA) in evaluating coarctation of aorta (CoA). |
23 patients were diagnosed with CoA, 12 cases had focal stenosis of aorta, while 11 had tubular stenosis. 19 cases were associated with other cardiovascular malformations, including 5 cases of hypoplastic aortic arch, 5 of patent ductus arteriosus, 10 of ventricular septal defect, 2 of bicuspid aortic valve, 4 of collateral arteries, 2 of aberrant left subclavian artery and 2 of persistent left superior vena cava, respectively. The mean diameter of stenotic segment of aorta was (7.0 +/- 3.7) mm. In 9 patients with tubular CoA, the diameter and length of stenotic segment of aorta were (6.2 +/- 7. 3) mm and (29.2 +/- 5.9) mm, respectively. The accuracies of DSCTA and TTE in the diagnosis of CoA were 100% and 91.3% (P > 0.05), respectively. |
4 |
| 19. Budoff MJ, Shittu A, Roy S. Use of cardiovascular computed tomography in the diagnosis and management of coarctation of the aorta. J Thorac Cardiovasc Surg. 146(1):229-32, 2013 Jul. |
Review/Other-Dx |
N/A |
To present various forms of coarctation of the aorta on cardiac computed tomography. |
No results stated in abstract. |
4 |
| 20. Sun Z. Diagnostic value of color duplex ultrasonography in the follow-up of endovascular repair of abdominal aortic aneurysm. J Vasc Interv Radiol. 2006; 17(5):759-764. |
Meta-analysis |
21 studies |
To systematically review the findings of diagnostic value of color duplex US in the follow-up of endovascular repair of AAAs. |
Pooled estimates of sensitivity, specificity, PPV, NPV, and accuracy of color duplex US compared with CTA (with 95% CI) were 66% (52%-81%), 93% (89%-97%), 76% (65%-87%), 90% (86%-95%), and 91% (86%-97%), respectively, for unenhanced color duplex US; and 81% (52%-100%), 82% (68%-97%), 58% (26%-90%), 95% (87%-100%), and 98% (91%-100%), respectively, for enhanced color duplex US. The sensitivity in the detection of endoleak was significantly improved with contrast material-enhanced color duplex US compared with unenhanced color duplex US (P<.05); however, no significant difference was found regarding the specificity, PPV, NPV, and accuracy between unenhanced and enhanced color duplex US (P>.05). Color duplex US was insensitive in measurement of aneurysm diameter compared with CTA in most situations. Color duplex US is not as accurate as CTA and cannot replace CTA in the follow-up of endovascular aortic repair of AAAs. However, the use of contrast material-enhanced color duplex US resulted in improvement of diagnostic accuracy in the detection of endoleak and warrants further study. |
M |
| 21. Thakkar AN, Chinnadurai P, Lin CH. Imaging adult patients with coarctation of the aorta. [Review]. Curr Opin Cardiol. 32(5):503-512, 2017 Sep. |
Review/Other-Dx |
N/A |
To provide an overview of current recommendations and techniques used to image coarctations of the aorta. |
No results stated in abstract. |
4 |
| 22. Russo V, Renzulli M, La Palombara C, Fattori R. Congenital diseases of the thoracic aorta. Role of MRI and MRA. [Review] [37 refs]. Eur Radiol. 16(3):676-84, 2006 Mar. |
Review/Other-Dx |
N/A |
To review the role of MRI and MRA in evaluation of congenital diseases of the thoracic aorta. |
No results stated in abstract. |
4 |
| 23. Allen BD, van Ooij P, Barker AJ, et al. Thoracic aorta 3D hemodynamics in pediatric and young adult patients with bicuspid aortic valve. J Magn Reson Imaging 2015;42:954-63. |
Observational-Dx |
30 pediatric and young adult patients with bicuspid aortic valve |
To evaluate the 3D hemodynamics in the thoracic aorta of pediatric and young adult bicuspid aortic valve (BAV) patients. |
There was a positive correlation with both mean and max AAo WSSsys and peak AAo velsys (mean: r = 0.84, P < 0.001, max: r = 0.94, P < 0.001) and AS (mean: rS = 0.43, P = 0.02, max: rS = 0.70, P < 0.001). AAo peak velocity was significantly higher when measured with echo compared with 4D flow MRI (2.1 ± 0.98 m/s versus 1.27 ± 0.49 m/s, P < 0.001). |
3 |
| 24. Burris NS, Hope MD. 4D flow MRI applications for aortic disease. Magn Reson Imaging Clin N Am 2015;23:15-23. |
Review/Other-Dx |
N/A |
To highlight ongoing research in the field of aortic 4D Flow imaging by focusing on promising quantitative hemodynamic markers of aortic disease. |
Many promising 4D Flow markers of aortic disease have been proposed, although larger prospective studies are needed to validate their clinical relevance. Within the next decade, 4D sequences may be commonly acquired during routine clinical cardiac MR studies, and provide valuable information to guide the medical and surgical management of patients with aortic disease. |
4 |
| 25. Ha H, Kim GB, Kweon J, et al. Hemodynamic Measurement Using Four-Dimensional Phase-Contrast MRI: Quantification of Hemodynamic Parameters and Clinical Applications. Korean J Radiol 2016;17:445-62. |
Review/Other-Dx |
N/A |
To discuss recent advances in 4D PC-MRI. |
No results stated. |
4 |
| 26. Camren GP, Wilson GJ, Bamra VR, Nguyen KQ, Hippe DS, Maki JH. A comparison between gadofosveset trisodium and gadobenate dimeglumine for steady state MRA of the thoracic vasculature. BioMed Research International. 2014:625614, 2014. |
Observational-Dx |
40 patients |
To retrospectively compare between gadofosveset trisodium and gadobenate dimeglumine steady state magnetic resonance angiography (SS-MRA) of the thoracic vasculature at 1.5T using signal-to-noise ratio (SNR) and vessel edge sharpness (ES) as markers of image quality. |
There was no significant difference in mean SNR for the gadofosveset or gadobenate groups (P values: 0.14 to 0.85). There was no significant difference in mean vessel ES for gadofosveset and gadobenate groups (P values: 0.17 to 0.78). |
3 |
| 27. Francois CJ, Tuite D, Deshpande V, Jerecic R, Weale P, Carr JC. Unenhanced MR angiography of the thoracic aorta: initial clinical evaluation. AJR Am J Roentgenol. 2008;190(4):902-906. |
Observational-Dx |
23 patients |
To determine if an unenhanced 3D segmented steady-state free precession (SSFP) MR angiography (MRA) technique would be an alternative to contrast-enhanced MR angiography (CE-MRA) for the evaluation of vasculature. |
The difference in orthogonal measurements of the aortic diameter between those made on images from the 3D SSFP and those made from the CE-MRA sequences was -0.042 cm. The aortic root was better visualized with 3D SSFP: score of 3.78 (of 5) for CE-MRA versus score of 4.65 (of 5) for 3D SSFP (p < 0.05). |
2 |
| 28. Ming Z, Yumin Z, Yuhua L, Biao J, Aimin S, Qian W. Diagnosis of congenital obstructive aortic arch anomalies in Chinese children by contrast-enhanced magnetic resonance angiography. J Cardiovasc Magn Reson. 2006; 8(5):747-753. |
Observational-Dx |
416 patients |
To evaluate the accuracy of contrast-enhanced MRA for the diagnosis of congenital obstructive aortic arch anomalies in children and compare it with TTE and other MRI techniques (ECG gated T1-weighted spin-echo imaging and gradient-echo cine imaging). |
The diagnostic sensitivity, specificity and accuracy of contrast-enhanced MRA for congenital obstructive aortic arch anomalies were 98% (208/213), 99% (201/203) and 98% (409/416), respectively. The diagnostic sensitivity, specificity and accuracy of TTE were 88% (187/213), 92% (186/203) and 90% (373/416), respectively. The diagnostic sensitivity, specificity and accuracy of other MRI techniques (ECG gated T1-weighted spin-echo imaging and gradient-echo cine imaging) were 89% (189/213), 84% (170/203) and 86% (359/416), respectively. |
3 |
| 29. Bogaert J, Kuzo R, Dymarkowski S, et al. Follow-up of patients with previous treatment for coarctation of the thoracic aorta: comparison between contrast-enhanced MR angiography and fast spin-echo MR imaging. Eur Radiol. 10(12):1847-54, 2000. |
Observational-Dx |
51 patients, 74 exams |
To compare the diagnostic value of contrast-enhanced ultrafast 3D MR angiography (CE MRA) with turbo or fast spin-echo (FSE) MRI in patients with previous treatment for aortic coarctation and to describe the findings encountered on routine follow-up exams done often years after treatment. |
Of 74 exams, six clinically important abnormalities were found: four aneurysms and two restenoses. Two small pseudoaneurysms were missed on the FSE studies. Contrast-enhanced MRA was judged to visualize aortic abnormalities better than FSE (47 of 74 MR studies) especially for the transverse aortic arch, coarctation site, left subclavian artery, and aortic arch configuration. For the ascending aorta and distal descending aorta, CE MRA and FSE performed equally well. Aortic diameters measured at four levels in the first 18 MRI studies showed no significant differences in diameter when measured by FSE or CE MRA (p = not significant) |
4 |
| 30. Jashari H, Rydberg A, Ibrahimi P, Bajraktari G, Henein MY. Left ventricular response to pressure afterload in children: aortic stenosis and coarctation: a systematic review of the current evidence. [Review]. Int J Cardiol. 178:203-9, 2015 Jan 15. |
Review/Other-Dx |
N/A |
To assess left ventricular (LV) function changes in infants, children and adolescents with congenital aortic stenosis (CAS) or Coarctation of Aorta (CoA) using various recent echocardiographic modalities including myocardial deformation imaging techniques as well as comparing LV function parameters between pre- and post-intervention among studies. |
No results stated in abstract. |
4 |
| 31. Singh S, Hakim FA, Sharma A, et al. Hypoplasia, pseudocoarctation and coarctation of the aorta - a systematic review. [Review]. Heart Lung Circ. 24(2):110-8, 2015 Feb. |
Review/Other-Dx |
N/A |
To present a systematic review of the published literature providing an evidence-based overview of hypoplasia, pseudocoarctation, and coarctation of the aorta. |
No results stated in abstract. |
4 |
| 32. Jaffe RB. Complete interruption of the aortic arch. 1. Characteristic radiographic findings in 21 patients. Circulation. 1975; 52(4):714-721. |
Observational-Dx |
21 patients |
To review the radiographs of patients to emphasize characteristic radiographic features previously not recognized. |
Rib notching, when present, in association with the above findings indicates a stenotic or closed ductus arteriosus with collateral circulation through intercostal arteries to the descending aorta. The bilateral or unilateral location, right or left side, of the notching is dependent on the site of interruption and origin of the subclavian arteries and may permit differentiation into types and subtypes on chest radiograph. |
4 |
| 33. Pickhardt PJ, Siegel MJ, Gutierrez FR. Vascular rings in symptomatic children: frequency of chest radiographic findings. Radiology. 1997; 203(2):423-426. |
Observational-Dx |
41 children |
To determine the relative frequency of radiographic findings in symptomatic children with vascular rings. |
Findings on 39 lateral radiographs included increased retrotracheal opacity on 31 (79%), anterior tracheal bowing on 36 (92%), and tracheal narrowing on 30 (77%) radiographs. All findings were present on 24 (62%) radiographs. Findings on 41 frontal radiographs included right aortic arch on 35 (85%), distal tracheal indentation on 30 (73%), and right descending aorta on 27 (66%) radiographs. All findings were present on 20 (49%) radiographs. Four (10%) frontal radiographs were normal or indeterminate. The combination of frontal and lateral views showed at least one abnormality in every patient. No symptomatic patient with a vascular ring had a normal radiograph. |
4 |
| 34. Jagannath AS, Sos TA, Lockhart SH, Saddekni S, Sniderman KW. Aortic dissection: a statistical analysis of the usefulness of plain chest radiographic findings. AJR Am J Roentgenol. 1986; 147(6):1123-1126. |
Observational-Dx |
36 patients |
To determine which findings were most useful in predicting aortic dissection. |
Widening of the mediastinum (P<.001) and widening of the aortic knob (P<.012) were the only two radiographic features of significance in predicting dissection. In a stepwise multiple logistic regression model, the radiologists achieved an overall accuracy of 85%, a sensitivity of 81%, and a specificity of 89%. Although this illustrates the usefulness of plain chest radiographs in diagnosing aortic dissection, poor interobserver agreement dictates that further definitive investigation be undertaken. |
2 |
| 35. Leonard JC, Hasleton PS. Dissecting aortic aneurysms: a clinicopathological study. I. Clinical and gross pathological findings. Q J Med. 1979; 48(189):55-63. |
Observational-Dx |
171 patients |
To evaluate the clinical and pathologic findings of patients with dissecting aortic aneurysms. |
Since treatment often varies with the site of dissection, aortography should be performed in most patients surviving the first few hours. Attention is drawn to the frequency (10.4 %) of multiple aortic lesions, and to the occasional aetiological significance of giant-cell arteritis, and, possibly, hypothyroidism. |
4 |
| 36. Connolly JE, Wilson SE, Lawrence PL, Fujitani RM. Middle aortic syndrome: distal thoracic and abdominal coarctation, a disorder with multiple etiologies. J Am Coll Surg. 194(6):774-81, 2002 Jun. |
Review/Other-Dx |
8 patients |
To examine patients with severe hypertension or claudication secondary to middle aortic coarctation using aortograms and provide treatment with vascular reconstruction procedures. |
Vascular reconstructions consisted of aortoaortic bypass, aortic resection with interposed grafting, reanastomotic resection of renal arteries into prosthetic grafts, and renal artery bypass with autogenous material. All eight patients' grafts have remained patent, with followups of 4 to 9 years, with relief of hypertension and claudication. Although Takayasu's disease can be progressive, aggressive surgical treatment in eight patients followed for 4 to 8 years postoperatively demonstrates that severe hypertension, claudication, or both are important indications for revascularization. |
4 |
| 37. Yan L, Li HY, Ye XJ, Xu RQ, Chen XY. Doppler ultrasonographic and clinical features of middle aortic syndrome. J Clin Ultrasound. 47(1):22-26, 2019 Jan. |
Observational-Dx |
11 patients with middle aortic syndrome (MAS) |
To discuss Doppler ultrasonographic and clinical features of middle aortic syndrome (MAS). |
The median age of 11 patients was 10 years (1-39 years). Ten patients presented with hypertension, only 2 cases presented with symptomatic intermittent claudication, and 1 case presented with abdominal pain. The ultrasonographic features of 11 patients with MAS included: (a) Gray-scale image showed significant segmental narrowing of the aorta in 9 cases. (b) Color Doppler demonstrated aliasing in the suspicious narrowed vessels of all cases. (c) On Spectral Doppler image, peak systolic velocity in the location of aorta coarctation was significantly elevated (range, 2.3~4.8 m/s). When infrarenal aorta was involved, a tardus parvus waveform was only seen in the distal aorta. When suprarenal or inter-renal aorta was involved, a tardus-parvus pattern was seen in the distal aorta as well as renal artery. |
4 |
| 38. Tonkin IL. The definition of cardiac malpositions with echocardiography and computed tomography. In: Friedman WF, Higgins CB, eds. Pediatric cardiac imaging. Philadelphia, Pa: Saunders; 1984:157-87. |
Review/Other-Dx |
N/A |
N/A |
No abstract available. |
4 |
| 39. Evangelista A, Avegliano G, Aguilar R, et al. Impact of contrast-enhanced echocardiography on the diagnostic algorithm of acute aortic dissection. Eur Heart J. 2010;31(4):472-479. |
Observational-Dx |
128 consecutive patients |
To determine the usefulness of contrast echocardiography in the diagnosis of AD and in the assessment of findings necessary for adequate patient management. |
Sensitivity and specificity of conventional TTE increased after contrast enhancement from 73.7% to 86.8% (P<0.005) and 71.2% to 90.4% (P<0.05), respectively. Sensitivity and specificity of enhanced TTE was similar to conventional TEE in ascending aorta (93.3% vs 95.6% and 97.6% vs 96.4%, respectively) and in the arch (88.4% vs 93.0% and 95.3% vs 98.82%, respectively). Contrast-enhanced TEE permitted the location of nonvisualized entry tear in 7 cases (10.6%), helped to correctly identify the true lumen in 6 (9.1%), and diagnosed retrograde dissection in 9 (13.6%). Contrast enhancement substantially improves TTE in the diagnosis of AD and should be considered as the initial imaging modality in the emergency setting. Contrast enhancement also has significant value for obtaining critical morphological and haemokinetic information by TEE useful for adequate patient management. |
2 |
| 40. Wyse RK, Robinson PJ, Deanfield JE, Tunstall Pedoe DS, Macartney FJ. Use of continuous wave Doppler ultrasound velocimetry to assess the severity of coarctation of the aorta by measurement of aortic flow velocities. Br Heart J. 52(3):278-83, 1984 Sep. |
Observational-Dx |
30 patients |
To determine whether Doppler ultrasound velocimetry might add clinically useful information for the non-invasive assessment of patients with coarctation of the aorta, a lesion which represents a form of obstruction rather different from the valvular stenoses. |
In the patients with unoperated coarctation the range of arm to leg systolic blood pressure gradients was 22-75 mm Hg. In postoperative patients this range was 4-50 mm Hg. In the control subjects the range was -10 to +5mm Hg. Of the 30 patients with coarctation, five had systolic pressures in the right arm that were greater than or equal to 60 mm Hg. In a further eight, this pressure was between 140 and 160 mm Hg. In patients with coarctation the peak flow velocity in the descending aorta was significantly higher than in the control subjects (p<0.001). There was no overlap between the two groups. The arm to leg systolic pressure gradient in patients with coarctation was plotted against peak descending aortic flow velocity; linear regression gave a coefficient of correlation of 0.84 (p<0.001). The arm to leg systolic pressure difference in these patients was also plotted against the pressure gradient predicted by the Doppler technique. There was a significant correlation between the two (r= 085; p<0.001). In patients with coarctation the peak flow velocity in the ascending aorta was significantly higher than in the control subjects (p<0.001) , and 83% of these values were above the range found in the control group. Two of the patients had both significant aortic stenosis and coarctation, whereas many others were known to have abnormalities of the aortic valve (such as bicuspid valve), which are commonly associated with coarctation. |
4 |
| 41. Karaosmanoglu AD, Khawaja RD, Onur MR, Kalra MK. CT and MRI of aortic coarctation: pre- and postsurgical findings. [Review]. AJR Am J Roentgenol. 204(3):W224-33, 2015 Mar. |
Review/Other-Dx |
N/A |
To summarize the roles of CT and MRI in the diagnosis and follow-up of patients with aortic coarctation. |
No results stated in abstract. |
4 |
| 42. Goldstein SA, Evangelista A, Abbara S, et al. Multimodality imaging of diseases of the thoracic aorta in adults: from the American Society of Echocardiography and the European Association of Cardiovascular Imaging: endorsed by the Society of Cardiovascular Computed Tomography and Society for Cardiovascular Magnetic Resonance. [Review]. J Am Soc Echocardiogr. 28(2):119-82, 2015 Feb. |
Review/Other-Dx |
N/A |
To summarize the fundamental role of the major noninvasive imaging techniques and the clinical acumen and suspicion, knowledge of imaging modalities for the assessment and management of the often life threatening diseases of the aorta. |
No results in abstract |
4 |
| 43. Houston A, Hillis S, Lilley S, Richens T, Swan L. Echocardiography in adult congenital heart disease. [Review] [87 refs]. Heart. 80 Suppl 1:S12-26, 1998 Nov. |
Review/Other-Dx |
N/A |
To review echocardiography in adult congenital heart disease. |
No abstract available. |
4 |
| 44. Barra L, Kanji T, Malette J, Pagnoux C, CanVasc. Imaging modalities for the diagnosis and disease activity assessment of Takayasu's arteritis: A systematic review and meta-analysis. [Review]. Autoimmun Rev. 17(2):175-187, 2018 Feb. |
Meta-analysis |
57 Studies |
To determine the effectiveness of imaging modalities for the management of Takayasu's Arteritis (TAK). |
From the 1126 citations screened, 57 studies met our inclusion criteria. Many of the studies were of small sample size (average N=27), cross-sectional design and low methodological quality. Ultrasound (US) had a lower pooled sensitivity (SN) of 81% (95% CI: 69-89%) than Magnetic Resonance Angiography (MRA) with SN=92% (95% CI: 88-95%) for TAK diagnosis (by clinical criteria and/or X-Ray angiography). Both had high specificities (SP) of >90% for TAK diagnosis. Fewer studies investigated computed tomography angiography (CTA), but SN and SP for TAK diagnosis was high (>90%). The utility of vessel wall thickening and enhancement by MRA and CTA to predict disease activity varied across studies. The pooled SN and SP of 18F-fluorodeoxyglucose-Positron Emission Tomography (FDG-PET) for disease activity was 81% (95% CI: 69-89%) and 74% (95% CI: 55-86%), respectively. |
Good |
| 45. Lin MP, Chang SC, Wu RH, Chou CK, Tzeng WS. A comparison of computed tomography, magnetic resonance imaging, and digital subtraction angiography findings in the diagnosis of infected aortic aneurysm. J Comput Assist Tomogr. 32(4):616-20, 2008 Jul-Aug. |
Observational-Dx |
21 patients |
To characterize imaging findings from CT, MRI, and angiogram in patients with infected aortic aneurysm. |
Maximal diameters were >10 cm in 2 patients (10%), 5 to 10 cm in 11 (52%), and <5 cm in 8 (38%). Average diameters were 6.5 cm in the aortic arch, 5.3 cm in the descending thoracic aorta and 5.1 cm in the abdominal aorta. Obvious aortic wall calcification occurred in 19 patients (90%). Other features included disrupted calcification (n=15; 71%), prominent and irregular wall thickening (n=17; 81%), periaortic soft tissue mass (n=15; 71%), rim enhancement (n=18; 86%), periaortic gas (n=7; 33%), periaortic stranding and fluid retention (n=14; 67%), periaortic hematoma (n=3; 14%), adjacent bone destruction (n=1; 5%), pleural effusion (n=12; 57%), and associated dissecting aneurysm (n=2; 10%). |
3 |
| 46. Hagspiel KD, Hunter YR, Ahmed HK, et al. Primary sarcoma of the distal abdominal aorta: CT angiography findings. Abdom Imaging. 29(4):507-10, 2004 Jul-Aug. |
Review/Other-Dx |
1 patient |
To present a case report of the computed tomographic angiographic (CTA) findings of a primary intimal abdominal aortic angiosarcoma. |
No results stated in abstract. |
4 |
| 47. Winter L, Langrehr J, Hanninen EL. Primary angiosarcoma of the abdominal aorta: multi-row computed tomography. Abdom Imaging. 35(4):485-7, 2010 Aug. |
Review/Other-Dx |
1 patient |
To present a case report of primary angiosarcoma of the aorta. |
The polyploid intimal alteration is clearly depicted on CT images. Morphology and the segmental obstruction of the aortic lumen without aneurysmal or extensive atherosclerotic mural changes should lead to the differential diagnosis of an intravascular malignancy. |
4 |
| 48. Macedo TA, Stanson AW, Oderich GS, Johnson CM, Panneton JM, Tie ML. Infected aortic aneurysms: imaging findings. Radiology. 231(1):250-7, 2004 Apr. |
Observational-Dx |
29 patients |
To determine the imaging characteristics of infected aortic aneurysms. |
Aneurysms were located in the ascending aorta (n=2, 6%), descending thoracic aorta (n=7, 23%), thoracoabdominal aorta (n=6, 19%), paravisceral aorta (n=2, 6%), juxtarenal aorta (n=3, 10%), infrarenal aorta (n=10, 32%), and renal artery (n=1, 3%). Two patients had two infected aortic aneurysms. CT revealed 25 saccular (93%) and two fusiform (7%) aneurysms with a mean diameter at initial discovery of 5.4 cm (range, 1-11 cm). Para-aortic soft-tissue mass, stranding, and/or fluid was present in 13 (48%) of 27 aneurysms, and early periaortic edema with rapid aneurysm progression and development was present in three (100%) patients with sequential studies. |
4 |
| 49. Rakita D, Newatia A, Hines JJ, Siegel DN, Friedman B. Spectrum of CT findings in rupture and impending rupture of abdominal aortic aneurysms. Radiographics. 2007; 27(2):497-507. |
Review/Other-Dx |
N/A |
To review CT findings of ruptured AAA. |
No results stated in abstract. |
4 |
| 50. Restrepo CS, Betancourt SL, Martinez-Jimenez S, Gutierrez FR. Aortic tumors. [Review]. Seminars in Ultrasound, CT & MR. 33(3):265-72, 2012 Jun. |
Observational-Dx |
N/A |
To review the pathophysiology and the clinical and imaging manifestations of these uncommon primary aortic tumors and more common secondary aortic tumors. |
Sarcomas are the most common primary tumors of the aorta and great vessels. Both CT and MRI are powerful imaging tools for the evaluation of these lesions. Imaging presentation varies depending on location, size, and growth pattern. Not infrequently, primary vascular tumors are erroneously diagnosed and treated as thrombotic disease, delaying the correct diagnosis and appropriate therapy. Subtle imaging features like contrast enhancement and increased metabolic activity may provide clues for the differentiation between tumor and thrombus. |
4 |
| 51. Yamada I, Nakagawa T, Himeno Y, Numano F, Shibuya H. Takayasu arteritis: evaluation of the thoracic aorta with CT angiography. Radiology. 209(1):103-9, 1998 Oct. |
Observational-Dx |
25 patients |
To determine the diagnostic accuracy of computed tomographic (CT) angiography in the evaluation of Takayasu arteritis. |
CT angiography clearly depicted various luminal changes, including stenosis, occlusion, dilatation, and aneurysm, in the thoracic aorta and its major branches. CT angiography accurately depicted 190 (95%) of 200 arteries, although the extent of the steno-occlusive lesions was overestimated in five (2%) and underestimated in five (2%). Furthermore, CT angiography depicted mural changes, including wall thickening, calcification, and mural thrombi, not seen with conventional angiography. The sensitivity and specificity of CT angiography in the diagnosis of Takayasu arteritis were 95% and 100%, respectively. |
4 |
| 52. Park JH, Chung JW, Lee KW, Park YB, Han MC. CT angiography of Takayasu arteritis: comparison with conventional angiography. J Vasc Interv Radiol. 8(3):393-400, 1997 May-Jun. |
Review/Other-Dx |
10 patients |
To compare computed tomography (CT) angiography with conventional angiography in the evaluation of the extent of disease in the aorta and its major branches in patients with Takayasu arteritis. |
Conventional angiography revealed 51 sites of luminal abnormalities. In five patients (50%), both conventional and MIP CT angiography depicted the same number of involved sites. At 36 of the 51 sites (71%), the estimation of luminal changes was the same for both modalities. In all patients, the transverse images provided additional mural findings in the aorta and its major branches. The integrated information provided by CT angiography, including MIP and transverse images, depicted more extensive disease than conventional angiography. |
4 |
| 53. Berthod PE, Aho-Glele S, Ornetti P, et al. CT analysis of the aorta in giant-cell arteritis: a case-control study. Eur Radiol. 28(9):3676-3684, 2018 Sep. |
Observational-Dx |
174 patients |
To assess aortic morphology by CT scan and its diagnostic value in giant cell arteritis (GCA). |
Aortic diameters and atheroma scores were similar between groups. Aortic wall thickness was greater in the GCA group, even after the exclusion of GCA patients with aortic wall thickness =3 mm. The receiver operating characteristic (ROC) curve showed that a wall thickness of 2.2 mm was the optimal threshold to diagnose GCA (sensitivity, 67%; specificity, 98%). |
3 |
| 54. Rajiah P, Schoenhagen P. The role of computed tomography in pre-procedural planning of cardiovascular surgery and intervention. Insights imaging. 4(5):671-89, 2013 Oct. |
Review/Other-Dx |
N/A |
To describe the role of CT in the pre-operative evaluation of patients undergoing cardiovascular surgeries and intervention with a pictorial review. |
CT scan is valuable in pre-operative evaluation for cardiac surgeries. Cardiovascular structures, including bypass grafts should be located >10 mm from the sternum in patients for reoperative cardiothoracic surgeries. Knowledge of variations in pulmonary venous anatomy are essential for planning radiofrequency ablation. |
4 |
| 55. Katabathina VS, Restrepo CS. Infectious and noninfectious aortitis: cross-sectional imaging findings. [Review]. Semin Ultrasound CT MR. 33(3):207-21, 2012 Jun. |
Review/Other-Dx |
N/A |
To discuss the role of wide array of imaging techniques in the diagnosis and management of aortitis and review the epidemiology, pathophysiology, imaging features, and prognoses of the wide spectrum of infectious and noninfectious aortitis. |
No results stated in abstract. |
4 |
| 56. de Boysson H, Dumont A, Liozon E, et al. Giant-cell arteritis: concordance study between aortic CT angiography and FDG-PET/CT in detection of large-vessel involvement. Eur J Nucl Med Mol Imaging. 44(13):2274-2279, 2017 Dec. |
Observational-Dx |
28 Patients |
To assess the concordance of aortic CT angiography (CTA) and FDG-PET/CT in the detection of large-vessel involvement at diagnosis in patients with giant-cell arteritis (GCA). |
We included 28 patients (21/7 women/men, median age 67 [56-82]). Nineteen patients had large-vessel involvement on PET/CT and 18 of these patients also presented positive findings on CTA. In a per-segment analysis, a median of 5 [1-7] and 3 [1-6] vascular territories were involved on positive PET/CT and CTA, respectively (p = 0.03). In qualitative analysis, i.e., positivity of the procedure suggesting a large-vessel involvement, the concordance rate between both procedures was 0.85 [0.64-1]. In quantitative analysis, i.e., per-segment analysis in both procedures, the global concordance rate was 0.64 [0.54-0.75]. Using FDG-PET/CT as a reference, CTA showed excellent sensitivity (95%) and specificity (100%) in a per-patient analysis. In a per-segment analysis, sensitivity and specificity were 61% and 97.9%, respectively. |
4 |
| 57. Hommada M, Mekinian A, Brillet PY, et al. Aortitis in giant cell arteritis: diagnosis with FDG PET/CT and agreement with CT angiography. Autoimmun Rev. 16(11):1131-1137, 2017 Nov. |
Observational-Dx |
79 patients (52 GCA patients and 27 controls) |
To assess the detection rate of aortitis in giant cell arteritis (GCA) with fluorodeoxyglucose positron emission tomography/computed tomography (PET) and to compare the findings with CT angiography (CTA). |
Aortitis was diagnosed using PET in 40% (14/35) of patients at diagnosis and in 0% of controls (0/27). Agreement was perfect between PET and CT at a patient-based level, and very good at a vascular segment-based level (kappa: 0.72 to 1). PET was positive in 35% (6/17) of patients scanned during GCA relapse, showing aortitis (n=4) and/or articular uptake (n=4). Discrepancies between PET and CT were observed only in relapsing GCA (n=3). Correlation between the maximum standardized uptake value and wall thickness was moderate at diagnosis (r: 0.57 to 0.7) and not statistically significant during relapse. |
3 |
| 58. Restrepo CS, Ocazionez D, Suri R, Vargas D. Aortitis: imaging spectrum of the infectious and inflammatory conditions of the aorta. [Review]. Radiographics. 31(2):435-51, 2011 Mar-Apr. |
Review/Other-Dx |
N/A |
To review the pathophysiology, epidemiology, imaging manifestations, and differential diagnoses of the different types of aortitis and their complications. |
Clinically, aortitis is characterized by nonspecific symptoms, leading to a complex diagnostic process; as a result, the condition isoften overlooked during the initial work-up of patients with constitutional symptoms and systemic disorders. A multimodality imaging approach is often required for assessment of both the aortic wall and aortic lumen, as well as for surveillance of disease activity and treatment planning. Cross-sectional imaging with multidetector CT and MR imaging has largely replaced conventional angiography for initial diagnosis and follow-up. Radiologists should be familiar with the clinical features and imaging findings associated with the different types of aortitis. |
4 |
| 59. Gornik HL, Creager MA. Aortitis. [Review] [128 refs]. Circulation. 117(23):3039-51, 2008 Jun 10. |
Review/Other-Dx |
N/A |
To review the pathophysiology, epidemiology, diagnostic, approach, and management of aortitis. |
No results stated in abstract. |
4 |
| 60. Blockmans D, Stroobants S, Maes A, Mortelmans L. Positron emission tomography in giant cell arteritis and polymyalgia rheumatica: evidence for inflammation of the aortic arch. Am J Med 2000;108:246-9. |
Observational-Dx |
69 patients |
To evaluate the use of positron emission tomography (PET) with 18F-glucose in conditions of which giant cell arteritis and polymyalgia rheumatica are characterized by laboratory signs of inflammation. |
Vascular uptake of 18F-glucose in the large thoracic arteries was significantly more common in patients with giant cell arteritis or polymyalgia rheumatica [14 of 25 (56%)] than control patients [1 of 44 (2%), P ,0.0001, Table 1). Vascular uptake in the arteries of the legs was seen in 16 of 25 (64%) patients with giant cell arteritis or polymyalgia rheumatica and in 10 of 44 (23%) controls (P ,0.001). Vascular 18F-glucose uptake in any location (thorax or legs) was seen in 19 of 25 patients (76%), compared with 10 of 44 controls (23%) (P ,0.0001). Of the 12 patients with giant cell arteritis or polymyalgia rheumatica who had predominantly systemic symptoms, including fever, 11 had vascular uptake, including 9 with uptake in the thoracic vessels. |
3 |
| 61. Morinobu A, Tsuji G, Kasagi S, et al. Role of imaging studies in the diagnosis and evaluation of giant cell arteritis in Japanese: report of eight cases. Mod Rheumatol. 21(4):391-6, 2011 Aug. |
Observational-Dx |
8 patients with giant cell arteritis (GCA) |
To clarify the characteristics and imaging results of Japanese patients with giant cell arteritis (GCA). |
No results stated in abstract. |
3 |
| 62. Lee YH, Choi SJ, Ji JD, Song GG. Diagnostic accuracy of 18F-FDG PET or PET/CT for large vessel vasculitis : A meta-analysis. [Review]. Z Rheumatol. 75(9):924-931, 2016 Nov. |
Meta-analysis |
8 studies |
To evaluate the diagnostic performance of 18F-fluorodeoxyglucose positron-emission tomography (18F-FDG PET) or positron-emission tomography/computed tomography (PET/CT) for patients with large vessel vasculitis. |
A total of eight studies involving 400 subjects (170 vasculitis patients and 230 controls) were selected for meta-analysis. The pooled sensitivity and specificity of 18F-FDG PET or PET/CT were 75.9?% (95?% confidence interval, CI 68.7-82.1) and 93.0?% (95?% CI 88.9-96.0), respectively. The positive likelihood ratio (PLR), negative likelihood ratio (NLR), and diagnostic odds ratio (DOR) were 7.267 (95?% CI 3.707-14.24), 0.303 (95?% CI 0.229-0.400), and 32.04 (95?% CI 13.08-78.45), respectively. The area under the curve (AUC) was 0.863 and the Q* index 0.794, indicating good diagnostic accuracy. There was no evidence of a threshold effect (Spearman's correlation coefficient =?0.120, p?=?0.776). When the data were limited to giant cell arteritis (GCA), the pooled sensitivity and specificity of 18F-FDG PET or PET/CT were 83.3?% (95?% CI 72.1-91.4) and 89.6?% (95?% CI 79.7-95.7), respectively; AUC was 0.884, and the Q* index 0.815, indicating modest accuracy with a small increase in diagnostic accuracy. |
Not Assessed |
| 63. Walter MA.. [(18)F]fluorodeoxyglucose PET in large vessel vasculitis. [Review] [65 refs]. Radiol Clin North Am. 45(4):735-44, viii, 2007 Jul. |
Review/Other-Dx |
N/A |
To summarize current information on the present clinical data and to assist nuclear medicine and rheumatology practitioners in recommending, performing, and interpreting the results of [18F]FDG-PET in patients with suspected large vessel vasculitis. |
No results stated in abstract. |
4 |
| 64. Zhang X, Zhou J, Sun Y, Shi H, Ji Z, Jiang L. 18F-FDG-PET/CT: an accurate method to assess the activity of Takayasu's arteritis. Clin Rheumatol. 37(7):1927-1935, 2018 Jul. |
Observational-Dx |
39 patients |
To investigate the value of 18F-fluorodeoxyglucose-positron emission tomography/computed tomography (18F-FDG-PET/CT) for assessment of the activity of Takayasu's arteritis (TA) and the correlation between acute-phase reactive proteins (ARPs) and standard uptake value (SUV). |
Analyses of the clinical characteristics and 42 18F-FDG-PET/CT scans in 39 TA patients were undertaken. The degree of FDG uptake in the blood vessel walls was assessed quantitatively by SUV. TA activity was analyzed by physician global assessment (PGA). Clinical and 18F-FDG-PET/CT characteristics were compared between patients with clinically active and clinically inactive TA. Maximum SUV (SUVmax), mean SUV (SUVmean), and SUV ratio (SUVratio) were significantly higher in the clinically active group than in the clinically inactive group (3.63?±?1.96 vs. 1.82?±?0.43, p?=?0.007; 2.07?±?0.71 vs. 1.43?±?0.32, p?=?0.009; 2.08?±?1.17 vs. 0.95?±?0.19, p?=?0.000). Analyses of receiver operating characteristic (ROC) curves revealed a cutoff value of SUVmax of 2.21, with sensitivity and specificity of 86.2 and 90.0%, respectively, for clinically active TA. The SUVratio cutoff was 1.27 with a sensitivity and specificity of 79.3 and 100.0%, respectively. |
3 |
| 65. Cullenward MJ, Scanlan KA, Pozniak MA, Acher CA. Inflammatory aortic aneurysm (periaortic fibrosis): radiologic imaging. Radiology. 159(1):75-82, 1986 Apr. |
Review/Other-Dx |
N/A |
To review radiologic imaging in preoperative diagnosis of aortic aneurysm. |
No results stated in abstract. |
4 |
| 66. Liu M, Liu W, Li H, Shu X, Tao X, Zhai Z. Evaluation of takayasu arteritis with delayed contrast-enhanced MR imaging by a free-breathing 3D IR turbo FLASH. Medicine (Baltimore). 96(51):e9284, 2017 Dec. |
Observational-Dx |
54 Patients
|
To observe delayed contrast-enhanced magnetic resonance imaging (DCE-MRI) in patients with Takayasu arteritis (TA) in comparison with magnetic resonance angiography (MRA). |
DCE-MRI was acquired with a free-breathing three-dimensional inversion recovery Turbo fast low-angle shot (3D IR Turbo FLASH). Neither stenosis nor delayed enhancement of arterial wall was shown in the control group. In patients with stable TA, arterial stenosis was observed on MRA. On DCE-MR, delayed enhancement of arterial walls could be observed in the active TA group but not in the stable TA group or the control group. Stenotic arteries on MRA were comparable in the active TA and stable TA (??=?2.70, P?=?.259); however, delayed enhancement of arterial walls in the active-TA group were more than those in the stable group (??=?27.00, P?<?.001). |
2 |
| 67. Atalay MK, Bluemke DA. Magnetic resonance imaging of large vessel vasculitis. [Review] [25 refs]. Curr Opin Rheumatol. 13(1):41-7, 2001 Jan. |
Review/Other-Dx |
N/A |
To review magnetic resonance (MR) methods applicable to Takayasu arteritis (TA) and giant cell arteritis (GCA). |
No results stated in abstract. |
4 |
| 68. Bley TA, Wieben O, Uhl M, Thiel J, Schmidt D, Langer M. High-resolution MRI in giant cell arteritis: imaging of the wall of the superficial temporal artery. AJR. 2005; 184(1):283-287. |
Observational-Dx |
20 patients |
To investigate the hypothesis that high-resolution MRI can reveal mural inflammatory changes of the superficial temporal artery in GCA. |
MRI sharply demonstrated the superficial temporal artery, allowing an evaluation of its lumen and wall. 17 patients were GCA-positive according to criteria of the American College of Rheumatology. Of these 17, 16 had true-positive MRI findings and one had false-negative MRI findings. The 3 patients who were GCA-negative according to the criteria had true-negative MRI findings. The mean thickness of the vessel wall and the lumen diameter were 0.88 +/- 0.23 mm and 0.78 +/- 0.29 mm, respectively, in GCA-positive patients and 0.57 +/- 0.25 mm and 0.7 +/- 0.1 mm, respectively, in GCA-negative patients. |
3 |
| 69. Koenigkam-Santos M, Sharma P, Kalb B, et al. Magnetic resonance angiography in extracranial giant cell arteritis. J. clin. rheumatol.. 17(6):306-10, 2011 Sep. |
Observational-Dx |
28 patients |
To retrospectively review extracranial involvement in patients with giant cell arteritis (GCA) and/or polymyalgia rheumatica (PMR), evaluated with magnetic resonance imaging (MRI), especially 3-dimensional contrast-enhanced magnetic resonance angiography images of the aortic arch and its branches. |
Both readers described vascular alterations in keeping with extracranial GCA in 19 of 28 patients (67%) with good interobserver agreement (k = 0.73) and with even higher agreement on diagnosing nonocclusive versus occlusive disease (k = 1.00). The most common lesions were bilateral axillary stenosis or obstructions, observed by both readers in 8 patients (28%). Among the 19 patients with magnetic resonance angiography lesions in the subclavian/axillary arteries, 12 (75%) had biopsy-proven GCA, but only 5 (41%) of these patients had clinical features of large artery disease. |
4 |
| 70. Siemonsen S, Brekenfeld C, Holst B, Kaufmann-Buehler AK, Fiehler J, Bley TA. 3T MRI reveals extra- and intracranial involvement in giant cell arteritis. Ajnr: American Journal of Neuroradiology. 36(1):91-7, 2015 Jan.AJNR Am J Neuroradiol. 36(1):91-7, 2015 Jan. |
Review/Other-Dx |
28 patients |
To prospectively assess the intracranial extent of vasculitic changes in patients with giant cell arteritis using a dedicated MR imaging protocol optimized for assessment of mural changes of intracranial arteries. |
Twenty patients had giant cell arteritis; 9 cases were biopsy-proved. Clear vessel wall enhancement of superficial extracranial and intradural internal carotid arteries was detected in 16 and 10 patients, respectively. Slight vessel wall enhancement of the vertebral arteries was seen. Of 9 patients with giant cell arteritis with vessel occlusion or stenosis, 2 presented with cerebral ischemic infarcts. Vessel occlusion or stenosis site coincided with the location of vessel wall enhancement of the vertebral arteries in 4 patients and of the intradural ICA in 1 patient. |
4 |
| 71. Rajiah P.. CT and MRI in the Evaluation of Thoracic Aortic Diseases. [Review]. Int J Vasc Med. 2013:797189, 2013. |
Review/Other-Dx |
N/A |
To describe and illustrate CT and MRI appearances of various acquired thoracic aortic conditions. |
No results stated in abstract. |
4 |
| 72. Mohsen NA, Haber M, Urrutia VC, Nunes LW. Intimal sarcoma of the aorta. AJR Am J Roentgenol. 175(5):1289-90, 2000 Nov. |
Review/Other-Dx |
1 patient |
To present a case report of intimal sarcoma of the aorta. |
No abstract available. |
4 |
| 73. Halbach C, McClelland CM, Chen J, Li S, Lee MS. Use of Noninvasive Imaging in Giant Cell Arteritis. [Review]. Asia-Pacific Journal of Ophthalmology. 7(4):260-264, 2018 Jul-Aug.Asia Pac J Ophthalmol (Phila). 7(4):260-264, 2018 Jul-Aug. |
Review/Other-Dx |
N/A |
To review the evidence for and against the value of nonophthalmic, noninvasive testing versus temporal artery biopsy (TAB) in the diagnosisof giant cell arteritis (GCA). |
No results stated in abstract. |
4 |
| 74. Zachrisson H, Svensson C, Dremetsika A, Eriksson P. An extended high-frequency ultrasound protocol for detection of vessel wall inflammation. Clin Physiol Funct Imaging. 38(4):586-594, 2018 Jul. |
Observational-Dx |
58 Patients |
To evaluate an extended protocol of the large vessels using high-frequency duplex ultrasound (DUS) for detection of vessel wall inflammation. |
The DUS findings showed normal vessels (n = 14), arteritis and atherosclerosis (n = 13), atherosclerosis (n = 15) and arteritis (n = 16). The latter group had a significant increased IMT in the common femoral artery and the common carotid artery (mean 1·0 ± SD 0·3 mm versus 0·6 ± 0·2 mm in the normal group (n = 37), P<0.00001, 1.2 ± 0.5 mm versus 0.8 ± 0.2 mm in the normal group (n = 40), P<0.00001). In the groups with sonographic signs implying arteritis (n = 29), 20 patients had a clinical diagnosis of arteritis, whereas eight patients had another main diagnosis such as malignancy/other inflammatory or infectious disease complicated by inflammation of the vessel wall. One patient had multiple diagnoses and was not possible to classify. |
4 |
| 75. Schmidt WA.. Ultrasound in the diagnosis and management of giant cell arteritis. [Review]. Rheumatology (Oxford). 57(suppl_2):ii22-ii31, 2018 02 01. |
Review/Other-Dx |
N/A |
To review the role of ultrasound in the diagnosis and management of giant cell arteritis. |
No results stated in abstract. |
4 |
| 76. Kankilic N, Aslan A, Karahan O, Demirtas S, Caliskan A, Yavuz C. Investigation of the arterial intima-media thickness in Behcet's disease patients without vascular complaints. Vascular. 26(4):356-361, 2018 Aug. |
Observational-Dx |
40 Patients |
To investigate the relationship between the intima-media thickness of the major arteries, in addition to other factors affecting the disease process, in Behcet’s disease without vascular involvement. |
There were no significant differences between the arterial intima-media thickness values of the Behcet’s disease patients and those of the control group (p > 0.05). However, there was a significant difference between the neutrophil–lymphocyte ratio (p = 0.004), low-density lipoprotein (p = 0.007), and triglyceride (p = 0042) levels of the two groups. Significant correlations were found between intima-media thickness and neutrophil–lymphocyte ratio levels (p = 0.012) and the disease duration (p = 0.030). There was also a significant correlation between the intima-media thickness of the femoral artery and disease duration (p = 0.014). |
4 |
| 77. Litmanovich D, Bankier AA, Cantin L, Raptopoulos V, Boiselle PM. CT and MRI in diseases of the aorta. AJR Am J Roentgenol 2009;193:928-40. |
Review/Other-Tx |
N/A |
To review the role of CT and MRI in the diagnosis, follow-up, and surgical planning of aortic aneurysms and acute aortic syndromes, including aortic dissection, intramural hematoma, and penetrating aortic ulcer. Also provide a systematic approach to the definition, causes, natural history, and imaging principles of these diseases. |
No results stated in the abstract. |
4 |
| 78. Liisberg M, Diederichsen AC, Lindholt JS. Abdominal ultrasound-scanning versus non-contrast computed tomography as screening method for abdominal aortic aneurysm - a validation study from the randomized DANCAVAS study. BMC med. imaging. 17(1):14, 2017 02 14. |
Experimental-Dx |
533 patients |
To validate non-contrast-enhanced computed tomography (nCT) compared to ultrasound sonography (US) as a screening method for abdominal aortic aneurysm (AAA) screening. |
Due to logistics, 533 underwent both nCT and US. In four patients, aortae could not be visualized with US, and two of these had an AAA (>30 mm) as diagnosed by nCT. Using nCT 30 (5.7%, 95% CI: 4.2;7.5%) AAA were found. US failed to detect 9 of these, but diagnosed 3 other cases, resulting prevalence by US was 4.5% (95% CI: 3.0;6.6%). Additionally, 5 isolated iliac aneurysms (=20 mm) (0.9%, 95% CI: 0.3;2.2%) were discovered by nCT. US performed reasonably, with sensitivity ranging from 57.1–70.4%, specificity however, ranged higher 99.2–99.6%. Comparably nCT performed with sensitivity ranging from 82.6–88.9%, nCTs specificity however ranged from 97.7–98. 4%. Analysis showed good correlations with no tendency to increasing variance with increasing diameter, and no significant differences between nCT and US with means varying slightly in both axis. |
2 |
| 79. Horinaka S, Yagi H, Fukushima H, Shibata Y, Takeshima H, Ishimitsu T. Associations Between Cardio-Ankle Vascular Index and Aortic Structure and Sclerosis Using Multidetector Computed Tomography. Angiology. 68(4):330-338, 2017 Apr. |
Observational-Dx |
98 patients |
To define the relationship between cardio-ankle vascular index (CAVI) and aortic atherosclerosis or structure on multidetector computed tomography (MDCT). |
Multivariate analysis showed that the vessel diameter of the ascending and descending aorta on MDCT depends on age, body surface area, and diastolic BP. The CAVI significantly correlated with the vessel diameter ( r = .453) and wall thickness ( r = .387) of the thoracic descending aorta ( P < .001, respectively). The CAVI was an independent predictor of the descending aortic wall thickness on multiple stepwise regression analysis. These data suggest that CAVI, a simple index, is useful for evaluating thoracic aortic atherosclerosis. |
2 |
| 80. Criqui MH, Aboyans V, Allison MA, et al. Peripheral Artery Disease and Aortic Disease. [Review]. Glob Heart. 11(3):313-326, 2016 09. |
Review/Other-Dx |
6,814 patients |
To study of the epidemiology and prognosis of several different measures of subclinical cardiovascular disease (CVD), as well as the progression of subclinical CVD, and their predictive role in clinical CVD |
No results stated in abstract. |
4 |
| 81. Criqui MH, Denenberg JO, McClelland RL, et al. Abdominal aortic calcium, coronary artery calcium, and cardiovascular morbidity and mortality in the Multi-Ethnic Study of Atherosclerosis. Arterioscler Thromb Vasc Biol. 34(7):1574-9, 2014 07. |
Observational-Dx |
1,974 patients |
To evaluate the predictive value of abdominal aortic calcium (AAC) for incident cardiovascular disease (CVD) independent of coronary artery calcium (CAC). |
We evaluated the association of AAC with CVD in 1974 men and women aged 45 to 84 years randomly selected from the Multi-Ethnic Study of Atherosclerosis participants who had complete AAC and CAC data from computed tomographic scans. AAC and CAC were each divided into following 3 percentile categories: 0 to 50th, 51st to 75th, and 76th to 100th. During a mean of 5.5 years of follow-up, there were 50 hard coronary heart disease events, 83 hard CVD events, 30 fatal CVD events, and 105 total deaths. In multivariable-adjusted Cox models including both AAC and CAC, comparing the fourth quartile with the =50th percentile, AAC and CAC were each significantly and independently predictive of hard coronary heart disease and hard CVD, with hazard ratios ranging from 2.4 to 4.4. For CVD mortality, the hazard ratio was highly significant for the fourth quartile of AAC, 5.9 (P=0.01), whereas the association for the fourth quartile of CAC (hazard ratio, 2.1) was not significant. For total mortality, the fourth quartile hazard ratio for AAC was 2.7 (P=0.001), and for CAC, it was 1.9, P=0.04. Area under the receiver operating characteristic curve analyses showed improvement for both AAC and CAC separately, although improvement was greater with CAC for hard coronary heart disease and hard CVD, and greater with AAC for CVD mortality and total mortality. Sensitivity analyses defining AAC and CAC as continuous variables mirrored these results. |
3 |
| 82. Craiem D, Chironi G, Casciaro ME, Graf S, Simon A. Calcifications of the thoracic aorta on extended non-contrast-enhanced cardiac CT. PLoS ONE. 9(10):e109584, 2014. |
Observational-Dx |
970 patients |
To investigate the prevalence and spatial distribution of Thoracic aorta calcium (TAC) all along the thoracic aorta (TA), to see how those segments that remain invisible in standard TA evaluation were affected. |
A total of 970 patients (77% men) underwent extended non-contrast cardiac CT scans including the aortic arch. An automated algorithm was designed to extract the vessel centerline and to estimate the vessel diameter in perpendicular planes. Then, calcifications were quantified using the Agatston score and associated with the corresponding thoracic aorta segment. The aortic arch and the proximal descending aorta, “invisible” in routine CAC screening, appeared as two vulnerable sites concentrating 60% of almost 11000 calcifications. The aortic arch was the most affected segment per cm length. Using the extended measurement method, TAC prevalence doubled from 31% to 64%, meaning that 52% of patients would escape detection with a standard scan. In a stratified analysis for CAC and/or TAC assessment, 111 subjects (46% women) were exclusively identified with the enlarged scan. |
3 |
| 83. Bos D, Leening MJ, Kavousi M, et al. Comparison of Atherosclerotic Calcification in Major Vessel Beds on the Risk of All-Cause and Cause-Specific Mortality: The Rotterdam Study. Circ Cardiovasc Imaging. 8(12), 2015 Dec. |
Observational-Dx |
2408 patients |
To compare the association of atherosclerosis in 4 different vessel beds, including the intracranial carotid arteries, with all-cause and cause-specific mortality providing crucial insight into which location of atherosclerosis carries the greatest risk of mortality. |
During 15775 person-years of follow-up, 283 participants died. Larger calcification volumes in all vessels were related to higher risks of all-cause mortality, cardiovascular, and noncardiovascular mortality, independent of cardiovascular risk factors. Most prominent associations were found for aortic arch calcification and cardiovascular mortality (age- and sex-adjusted hazard ratio per 1-SD increase 2.72 [95% confidence interval, 1.85– 4.02]), independent of calcification elsewhere (hazard ratio, 1.75 (95% confidence interval, 1.13–2.72]). Calcification in any vessel improved prediction for all 3 outcomes. |
3 |
| 84. Galaska R, Kulawiak-Galaska D, Wegrzyn A, et al. Assessment of Subclinical Atherosclerosis Using Computed Tomography Calcium Scores in Patients with Familial and Nonfamilial Hypercholesterolemia. J Atheroscler Thromb. 23(5):588-95, 2016 May 02. |
Observational-Dx |
139 patients |
To compare coronary calcium scores and aortic calcium scores between patients with severe hypercholesterolemia having a DNA-based diagnosis of FH (FH group) versus patients with severe hypercholesterolemia without the FH gene mutation (NFH group). |
TCSasc (CCS and TCS in ascending aorta) was significantly higher in the FH group when compared to the NFH group (30.6± 59 vs 4.7±13.4, p<0.001. After adjusting for age, sex, smoking, blood pressure, history of diabetes mellitus and LDL cholesterol levels, FH gene mutation was an independent risk factor of having non-zero TCSasc 3.6 (95% CI, 1.4-9.5, p<0.01), high TCSasc 9.6 (95% CI, 2.4-38.2, p<0.01) and high CCS of 4.1 (95% CI, 1.2-13.2. p<0.05). |
2 |
| 85. Hiratzka LF, Bakris GL, Beckman JA, et al. 2010 ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM Guidelines for the diagnosis and management of patients with thoracic aortic disease. A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, American Association for Thoracic Surgery, American College of Radiology,American Stroke Association, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of Thoracic Surgeons,and Society for Vascular Medicine. J Am Coll Cardiol. 2010;55(14):e27-e129. |
Review/Other-Tx |
N/A |
To report guidelines on thoracic aortic disease. |
No results in abstract. |
4 |
| 86. Fernandez JD, Donovan S, Garrett HE, Jr., Burgar S. Endovascular thoracic aortic aneurysm repair: evaluating the utility of intravascular ultrasound measurements. J Endovasc Ther. 2008; 15(1):68-72. |
Observational-Dx |
33 patients |
To compare IVUS and CT measurements of aortic diameter for the determination of stent-graft sizes used in TEVAR. |
IVUS measurements of the thoracic aorta were larger than CT measurements 66% of the time. However, there are 2 concerns with IVUS: off-center measurements distort the image and tangential measurements on a curve do not reflect a true centerline diameter. Thus, off-center IVUS measurements or those taken in the tortuous portion of the aorta may not be as accurate as centerline CT measurements. |
2 |
| 87. Hansen NJ.. Computed Tomographic Angiography of the Abdominal Aorta. [Review]. Radiol Clin North Am. 54(1):35-54, 2016 Jan. |
Review/Other-Dx |
N/A |
To discuss Computed tomographic (CT) angiography (CTA) and its imaging features of disease processes, inflammatory vasculitides, and occlusive athersclerotic disease. |
No results stated in abstract. |
4 |
| 88. Schertler T, Frauenfelder T, Stolzmann P, et al. Triple rule-out CT in patients with suspicion of acute pulmonary embolism: findings and accuracy. Acad Radiol. 16(6):708-17, 2009 Jun. |
Observational-Dx |
125 patients |
To prospectively investigate the diagnostic value of triple rule-out CT in patients suspected of having acute pulmonary embolism. |
Triple rule-out CT was normal in 53 (42%) patients. Overall sensitivity, specificity, and PPV and NPV of triple rule-out CT for cardiovascular disease were 100% (95% CI, 90%-100%), 98% (95% CI, 94%-100%), 95% (95% CI, 82%-99%), and 100% (95% CI, 97%-100%, respectively). |
1 |
| 89. Tanahashi Y, Goshima S, Kondo H, et al. Additional value of venous phase added to aortic CT angiography in patients with aortic aneurysm. Clin Imaging. 44:51-56, 2017 Jul - Aug. |
Observational-Dx |
240 CT images |
To compare diagnostic performance of unenhanced and CTA images (Image set 1) to that of combined unenhanced, CTA, and venous-phase images (Image set 2) for incidentalomas in patients with aortic aneurysm. |
Sensitivity was higher in Image set 2 than Image set 1 in observer 1 and overall (P=0.03 and 0.00). AUCs for both observers were higher in Image set 2 than Image set 1 (P=0.03 and 0.01). |
3 |
| 90. Lu TL, Huber CH, Rizzo E, Dehmeshki J, von Segesser LK, Qanadli SD. Ascending aorta measurements as assessed by ECG-gated multi-detector computed tomography: a pilot study to establish normative values for transcatheter therapies. Eur Radiol. 2009; 19(3):664-669. |
Observational-Dx |
77 patients |
To provide an insight into normative values of the ascending aorta in regards to novel endovascular procedures using ECG-gated multi-detector CTA. |
Mean distances (mm) were: from the plane passing through the proximal insertions of the aortic valve cusps to the right brachio-cephalic artery 92.6 +/- 11.8, from the plane passing through the proximal insertions of the aortic valve cusps to the proximal coronary ostium 12.1 +/- 3.7, and between both coronary ostia 7.2 +/- 3.1, minimal arc of the ascending aorta from left coronary ostium to right brachio-cephalic artery 52.9 +/- 9.5, and the fibrous continuity between the aortic valve and the anterior leaflet of the mitral valve 14.6 +/- 3.3, coefficients of variation 13%-43%. Mean aortic valve area was 582.0 +/- 131.9 mm(2). The variation of the antero-posterior and transverse diameters of the ascending aorta during the cardiac cycle were 8.4% and 7.3%, respectively. Results showed large inter-individual variations in diameters and distances but with limited intra-individual variations during the cardiac cycle. A personalized approach for planning endovascular devices must be considered. |
3 |
| 91. Ocak I, Lacomis JM, Deible CR, Pealer K, Parag Y, Knollmann F. The aortic root: comparison of measurements from ECG-gated CT angiography with transthoracic echocardiography. J Thorac Imaging. 2009; 24(3):223-226. |
Observational-Dx |
68 patients |
To compare the measurements of the aortic root obtained from ECG-gated CTA to the measurements obtained from TTE. |
The average aortic root diameter measured by TTE was 33 +/- 4.1 mm; on CTA it was 36.9 +/- 3.8 mm. The median difference between the 2 measurements was 3.9 mm which was significant (P<0.0001). In patients whose aortic root measurements with CTA were normal, the TTE measurements were also normal. However, in the group of patients with dilated aortic roots by CTA, TTE measurements were significantly lower and many were normal. In the group of patients with dilated aortic root by TTE, the CTA measurements of the aortic root were similarly increased. |
4 |
| 92. Li N, Beck T, Chen J, et al. Assessment of thoracic aortic elasticity: a preliminary study using electrocardiographically gated dual-source CT. Eur Radiol. 2011; 21(7):1564-1572. |
Observational-Dx |
56 subjects |
To gain a new insight into the elastic properties of the thoracic aorta in patients without aortic diseases using ECG-gated dual-source CT. |
Aortic diameter changes were noted throughout the cardiac cycle. The maximum average diameter was seen at an RR interval of 24.02 +/- 4.99% for the ascending aorta and 25.63 +/-4.77% for the descending aorta. The minimum was at 93.5 +/- 4.04% for the ascending aorta and 96.6 +/- 4.58% for the descending aorta. There was an age-dependent decrease in elasticity, while different correlation coefficients were found between various age groups and different elastic parameters. |
3 |
| 93. Agarwal PP, Chughtai A, Matzinger FR, Kazerooni EA. Multidetector CT of thoracic aortic aneurysms. Radiographics 2009;29:537-52. |
Review/Other-Dx |
N/A |
To discuss and illustrate common and uncommon thoracic aortic aneurysms (TAAs) with an emphasis on their causes, significance, computedtomographic (CT) features, and potential complications. |
No results stated in abstract. |
4 |
| 94. Bhave NM, Nienaber CA, Clough RE, Eagle KA. Multimodality Imaging of Thoracic Aortic Diseases in Adults. [Review]. JACC Cardiovasc Imaging. 11(6):902-919, 2018 06. |
Review/Other-Dx |
N/A |
To discuss the various modalities used to diagnose and follow-up on patients with acute aortic syndromes (AAS) and thoracic aortic aneurysms (TAA). |
No results stated in abstract. |
4 |
| 95. Erbel R, Aboyans V, Boileau C, et al. 2014 ESC Guidelines on the diagnosis and treatment of aortic diseases: Document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult. The Task Force for the Diagnosis and Treatment of Aortic Diseases of the European Society of Cardiology (ESC). Eur Heart J. 35(41):2873-926, 2014 Nov 01. |
Review/Other-Tx |
N/A |
Guidance document on the diagnosis, methods for imaging, and treatment of aortic diseases. |
No results in abstract. |
4 |
| 96. Aghayev A, Giannopoulos AA, Gronsbell J, et al. Common First-Pass CT Angiography Findings Associated With Rapid Growth Rate in Abdominal Aorta Aneurysms Between 3 and 5 cm in Largest Diameter. AJR Am J Roentgenol. 210(2):431-437, 2018 Feb. |
Observational-Dx |
140 patients |
To describe CT angiography (CTA) findings of lumen contrast heterogeneity and intraluminal thrombus volume and to evaluate their relationship with rapid aneurysm growth in patients with abdominal aortic aneurysms (AAA) between 3 and 5 cm. |
Using a baseline logistic regression model, lumen contrast heterogeneity (odds ratio [OR], 1.16; 95% CI, 1.05-1.32), intraluminal thrombus volume (OR, 2.15; 95% CI, 1.26-3.86), and maximum AAA diameter (OR, 1.69; 95% CI, 1.03-2.84) were independently associated with increased likelihood of rapid aneurysm growth. None of the patient comorbidities or medications were significantly associated with the outcome when added to the baseline model. |
3 |
| 97. Muluk SL, Muluk PD, Shum J, Finol EA. On the Use of Geometric Modeling to Predict Aortic Aneurysm Rupture. Ann Vasc Surg. 44:190-196, 2017 Oct. |
Observational-Dx |
CT scans from 180 patients |
To identify a set of computed tomography (CT)-based geometric parameters that would better predict the risk of abdominal aortic aneurysm (AAA) rupture than using the maximum diameter (Dmax) of the aorta. |
Linear regression identified 40 correlates of rupture. Following stepwise backward elimination, we developed a multivariate logistic regression model containing 15 geometric parameters, including Dmax. This model was compared with a model containing Dmax alone. The multivariate model correctly classified 98% of all cases, whereas the Dmax-only model correctly classified 72% of cases. Receiver operating characteristic analysis showed that the multivariate model had an area under the curve of 0.995, as compared with 0.770 for the Dmax-only model. This difference was highly significant (P < 0.0001). |
4 |
| 98. Zha Y, Peng G, Li L, Yang C, Lu X, Peng Z. Quantitative Aortic Distensibility Measurement Using CT in Patients with Abdominal Aortic Aneurysm: Reproducibility and Clinical Relevance. Biomed Res Int. 2017:5436927, 2017. |
Observational-Dx |
54 patients |
To investigate the reproducibility of aortic distensibility (D) measurement using CT and assess its clinical relevance in patients with infrarenal abdominal aortic aneurysm (AAA). |
A mean distensibility of Dlevel??1. = (1.05 ± 0.22) × 10-5??Pa-1 and Dlevel??2. = (0.49 ± 0.18) × 10-5??Pa-1 was found. ICC proved excellent consistency between readers over two locations: 0.92 for intraobserver and 0.89 for interobserver difference in level 1. and 0.85 and 0.79 in level 2. Multivariate analysis of all these variables showed sac distensibility to be independently related (R2 = 0.68) to BMI, diastolic blood pressure, and AAA diameter. |
3 |
| 99. Youssefi P, Sharma R, Figueroa CA, Jahangiri M. Functional assessment of thoracic aortic aneurysms - the future of risk prediction?. [Review]. Br Med Bull. 121(1):61-71, 2017 01 01. |
Review/Other-Dx |
N/A |
To discuss the need of functional assessment of the aorta to help identify patients at risk of aortic complications, and to introduce new haemodynamic indices into management guidelines |
No results stated in abstract. |
4 |
| 100. Bogaert J, Meyns B, Rademakers FE, et al. Follow-up of aortic dissection: contribution of MR angiography for evaluation of the abdominal aorta and its branches. Eur Radiol. 7(5):695-702, 1997. |
Review/Other-Dx |
28 patients |
To evaluate whether MR angiography can provide a complete examination of the abdominal aorta. |
The presence of an intima flap and the re-entry site could be depicted in all MR studies. Thrombus in the false channel was seen in 8 studies. The origin of the abdominal visceral branches and their relation to the false-true channel could be depicted, except in 4 of 80 renal arteries studied. Extension of the dissection into the coeliac trunk was seen in 2 and in the superior mesenteric artery in 10 studies. Dilatation of the suprarenal abdominal aorta was seen in 20 studies, and of the infrarenal aorta in 9 studies. |
4 |
| 101. Pereles FS, McCarthy RM, Baskaran V, et al. Thoracic aortic dissection and aneurysm: evaluation with nonenhanced true FISP MR angiography in less than 4 minutes. Radiology. 2002;223(1):270-274. |
Observational-Dx |
29 patients |
To retrospectively evaluate single-shot true FISP and cine true FISP MR imaging of the thoracic aorta for the diagnosis of aortic dissection or aneurysm. |
Nonenhanced true fast imaging with steady-state precession MRI alone was 100% accurate for determining the presence or absence of dissection or aneurysm. |
3 |
| 102. Prince MR, Narasimham DL, Jacoby WT, et al. Three-dimensional gadolinium-enhanced MR angiography of the thoracic aorta. AJR Am J Roentgenol. 1996;166(6):1387-1397. |
Observational-Dx |
90 patients 97 MR exams, 4 observers |
To evaluate image quality and preliminary experience with 3D gadolinium enhanced MRA of thoracic aorta. All MR exams were evaluated retrospectively for intravascular signal-to-noise ratio. |
Signal-to-noise ratio highest in aortic arch, upper descending aorta, upper abdominal aorta. Stenosis of major branch vessel origins detected with sensitivity 90%, specificity 96%. Type of dissection correctly determined in all 8 dissection patients. 3D gadolinium-enhanced MRA has the potential to accurately diagnose AD, coarctation, and aneurysm. |
2 |
| 103. Summers RM, Andrasko-Bourgeois J, Feuerstein IM, et al. Evaluation of the aortic root by MRI: insights from patients with homozygous familial hypercholesterolemia. Circulation. 98(6):509-18, 1998 Aug 11. |
Observational-Dx |
29 subjects |
To evaluate the aortic root by use of MRI in 17 homozygous familial hypercholesterolemia (HFH) patients and 12 normal control subjects in a prospective, blinded, controlled study. |
Atherosclerotic plaque, visible on fat-suppressed images but never on water-suppressed images, was present in 9 HFH patients (53%). Supravalvular aortic stenosis was present in 7 patients with HFH (41%). Maximum supravalvular aortic wall thickness was significantly greater and OD and lumen cross-sectional area (CSA) were smaller in patients than in control subjects (P=0.006, 0.0005, and 0.06, respectively). Maximum wall thickness was associated with a greater calcium score on electron-beam CT (P=0.02). Although the cumulative exposure of the aortic root to cholesterol (the cholesterol-year score) was significantly correlated with the Achilles tendon CSA and vascular calcification, this score did not correlate with the wall thickness or aortic CSA. |
3 |
| 104. Summers RM, Sostman HD, Spritzer CE, Fidler JL. Fast spoiled gradient-recalled MR imaging of thoracic aortic dissection: preliminary clinical experience at 1.5 T. Magn Reson Imaging. 14(1):1-9, 1996. |
Observational-Dx |
28 Patients |
To evaluate fast spoiled gradient-recalled (FSPGR) magnetic resonance (MR) imaging in the diagnosis of thoracic aortic dissection (TAD). |
The average scanning time for the FSPGR images was approximately 1 min. Three readers interpreted the FSPGR images for the presence or absence of TAD. An ROC analysis was done. At a specificity of 90%, the sensitivity ranged from 52% to 90% for the three readers. Pulsatility artifacts and mural thrombus were causes of false-positive and false-negative readings. The areas under the ROC curves (Az) ranged from 0.85 to 0.97 for the three readers. There was a statistically significant difference in the Az values for two of the experienced readers (p = .02). The correct type of dissection was determined in only 65% of the true-positive diagnoses. |
3 |
| 105. Krishnam MS, Tomasian A, Deshpande V, et al. Noncontrast 3D steady-state free-precession magnetic resonance angiography of the whole chest using nonselective radiofrequency excitation over a large field of view: comparison with single-phase 3D contrast-enhanced magnetic resonance angiography. Invest Radiol. 2008; 43(6):411-420. |
Observational-Dx |
30 consecutive patients |
To evaluate the feasibility of 3D SSFP MRA using nonselective radiofrequency excitation in the assessment of cardiac morphology, thoracic aorta, main pulmonary, and proximal coronary arteries. |
On SSFP MRA, readers 1 and 2 graded 233 (97.1%) and 234 (97.5%) coronary arterial segments and cardiac chambers, and 275 (91.7%) and 278 (92.7%) noncoronary arterial segments with diagnostic definition (grades 2 and 3) (k = 0.86). On conventional contrast enhanced-MRA, readers 1 and 2 graded 10 (4.2%) and 12 (5%) coronary arterial segments and cardiac chambers, and 272 (90.7%) and 270 (90%) noncoronary arterial segments with diagnostic definition (grades 2 and 3) (k = 0.89). Segmental visibility was higher for aortic root, pulmonary trunk, proximal coronary arteries, and heart chambers (P<0.001), and lower for supra-aortic arteries (P<0.001) on SSFP MRA for each reader. Signal-to-noise ratio and contrast-to-noise ratio values were higher for aortic root and aorta on SSFP MRA (P<0.001 for both). No significant difference existed between signal-to-noise ratio and contrast-to-noise ratio values for the other vascular segments and cardiac chambers on SSFP and contrast enhanced-MRA (P>0.05 for all). The 2 readers demonstrated vascular stenosis and dilatation/aneurysm in 7 and 35 segments on both datasets, respectively. |
1 |
| 106. Krishnam MS, Tomasian A, Malik S, Desphande V, Laub G, Ruehm SG. Image quality and diagnostic accuracy of unenhanced SSFP MR angiography compared with conventional contrast-enhanced MR angiography for the assessment of thoracic aortic diseases. Eur Radiol. 20(6):1311-20, 2010 Jun. |
Observational-Dx |
50 patients |
To determine the image quality and diagnostic accuracy of 3-D unenhanced SSFP MRA for the evaluation of thoracic aortic diseases. |
Abnormal aortic findings, including aneurysm (n = 47), coarctation (n = 14), dissection (n = 12), aortic graft (n = 6), IMH (n = 11), mural thrombus in the aortic arch (n = 1), and penetrating aortic ulcer (n = 9), were confidently detected on both datasets. Sensitivity, specificity, and diagnostic accuracy of SSFP MRA for the detection of aortic disease were 100% with contrast enhanced-MRA serving as a reference standard. Image quality of the aortic root was significantly higher on SSFP MRA (P<0.001) with no significant difference for other aortic segments (P>0.05). Signal-to-noise ratio and contrast-to-noise ratio values were higher for all segments on SSFP MRA (P<0.01). |
3 |
| 107. Nienaber CA, von Kodolitsch Y, Brockhoff CJ, Koschyk DH, Spielmann RP. Comparison of conventional and transesophageal echocardiography with magnetic resonance imaging for anatomical mapping of thoracic aortic dissection. A dual noninvasive imaging study with anatomical and/or angiographic validation. Int J Card Imaging. 1994; 10(1):1-14. |
Observational-Dx |
35 consecutive patients |
To compare the diagnostic accuracy of 2D and color-coded Doppler echocardiography using the conventional TTE and TEE with MRI for the exact morphologic evaluation and anatomical mapping of the thoracic aorta. |
The results of each diagnostic method were validated independently against the 'gold standard' of intraoperative findings (n=17), necropsy (n=4) or contrast angiography (n=22). Compared to conventional TTE both TEE and MRI were more reliable in detecting aortic dissections (TTE vs TEE: P<0.02; TTE vs MRI: P<0.01) and associated epiphenomena. Moreover, the reliability of TTE decreased significantly from proximal to distal segments of the aorta, e.g. from the ascending segment to the arch (P<0.05) and to the descending aorta (P<0.005), whereas the sensitivities of both TEE and MRI were excellent irrespective of the site of dissection. |
1 |
| 108. Gottsegen JM, Coplan NL. The atherosclerotic aortic arch: considerations in diagnostic imaging. [Review] [39 refs]. Preventive Cardiology. 11(3):162-7, 2008. |
Review/Other-Dx |
N/A |
To highlight the significance of factors such as aortic plaque morphology, distribution, and severity related to the atheromatous aortic arch. |
No results stated in abstract. |
4 |
| 109. Corti R.. Noninvasive imaging of atherosclerotic vessels by MRI for clinical assessment of the effectiveness of therapy. [Review] [79 refs]. Pharmacology & Therapeutics. 110(1):57-70, 2006 Apr. |
Review/Other-Dx |
N/A |
To discuss less invasive imaging options of atherosclerosis. |
No results stated. |
4 |
| 110. Nagpal P, Khandelwal A, Saboo SS, Bathla G, Steigner ML, Rybicki FJ. Modern imaging techniques: applications in the management of acute aortic pathologies. [Review]. Postgraduate Medical Journal. 91(1078):449-62, 2015 Aug. |
Review/Other-Dx |
N/A |
To describe the imaging anatomy of the aorta, basic principles of relevant modern imaging techniques and the individual acute aortic pathologies with emphasis on their pathogenesis, imaging features and treatment options. |
No results stated in abstract. |
4 |
| 111. Avramovski P, Avramovska M, Lazarevski M, Sikole A. Femoral neck and spine bone mineral density-Surrogate marker of aortic calcification in postmenopausal women. Anatol J Cardiol. 16(3):202-9, 2016 Mar. |
Observational-Dx |
56 females |
To determine the accuracy of anterior-posterior (AP) dual-energy X-ray absorptiometry (DXA) compared with that of X-ray lateral lumbar radiography (LLR) in detecting and scoring AAC. |
The mean BMDFN was 0.744 ± 0.184 g/cm(2), and the mean BMDLS was 0.833 ± 0.157 g/cm(2) (p<0.0001); the mean ?BMD was 0.089 ± 0.077 g/cm(2), and the mean AAC score was 2.182 ± 1.982. Bivariate Pearson's correlation analysis revealed a significant positive correlation between AAC and ?BMD (r=0.449, p=0.0006); by linear regression analysis, R(2)=0.2019, and by multiple regression analysis, ßst=13.5244 (p<0.0001). We found a sensitivity of 64.3% and specificity of 82.9% by receiver operating characteristic [ROC; area under the ROC curve (AUC=0.759)] in the prediction of AAC by ?BMD. |
3 |
| 112. Bondonno NP, Lewis JR, Prince RL, et al. Fruit Intake and Abdominal Aortic Calcification in Elderly Women: A Prospective Cohort Study. Nutrients. 8(3):159, 2016 Mar 10. |
Observational-Dx |
1510 women |
To examine the cross-sectional relationship of total and individual fruit (apple, pear, orange and other citrus, and banana) intake with AAC, scored between 0 and 24. |
AAC scores were significantly negatively correlated with total fruit and apple intakes (p < 0.05), but not with pear, orange or banana intakes (p > 0.25). In multivariable-adjusted logistic regression, each standard deviation (SD; 50 g/day) increase in apple intake was associated with a 24% lower odds of having severe AAC (AAC score >5) (odd ratio OR): 0.76 (0.62, 0.93), p = 0.009). |
3 |
| 113. Lewis JR, Schousboe JT, Lim WH, et al. Abdominal Aortic Calcification Identified on Lateral Spine Images From Bone Densitometers Are a Marker of Generalized Atherosclerosis in Elderly Women. Arteriosclerosis, Thrombosis & Vascular Biology. 36(1):166-173, 2016 Jan. |
Observational-Dx |
892 elderly women |
To investigate whether this low-cost, minimal radiation technique (dual energy X-ray absorptiometry, or DXA) for assessing abdominal aortic calcification is related to an established test for generalized atherosclerosis presence and burden |
We investigated whether dual-energy x-ray absorptiometry-derived measures of AAC were related to an established test of generalized atherosclerosis in 892 elderly white women aged >70 years with images captured during bone density testing in 1998/1999 and B-mode carotid ultrasound in 2001. AAC scores were calculated using a validated 24-point scale into low (AAC24 score, 0 or 1), moderate (AAC24 scores, 2-5), and severe AAC (AAC24 scores, >5) seen in 45%, 36%, and 19%, respectively. AAC24 scores were correlated with mean and maximum common carotid artery intimal medial thickness (rs=0.12, P<0.001 and rs=0.14, P<0.001). Compared with individuals with low AAC, those with moderate or severe calcification were more likely to have carotid atherosclerotic plaque (adjusted prevalence ratio (PR), 1.35; 95% confidence interval, 1.14-1.61; P<0.001 and prevalence ratio, 1.94; 95% confidence interval, 1.65-2.32; P<0.001, respectively) and moderate carotid stenosis (adjusted prevalence ratio, 2.22; 95% confidence interval, 1.39-3.54; P=0.001 and adjusted prevalence ratio, 4.82; 95% confidence interval, 3.09-7.050; P<0.001, respectively). The addition of AAC24 scores to traditional risk factors improved identification of women with carotid atherosclerosis as quantified by C-statistic (+0.075, P<0.001), net reclassification (0.249, P<0.001), and integrated discrimination (0.065, P<0.001). |
2 |
| 114. Erbel R, Aboyans V, Boileau C, et al. [2014 ESC Guidelines on the diagnosis and treatment of aortic diseases]. [Polish]. Kardiologia Polska. 72(12):1169-252, 2014. |
Review/Other-Dx |
N/A |
N/A |
No results stated. |
4 |
| 115. Argyriou C, Georgiadis GS, Kontopodis N, et al. Screening for Abdominal Aortic Aneurysm During Transthoracic Echocardiography: A Systematic Review and Meta-analysis. [Review]. Eur J Vasc Endovasc Surg. 55(4):475-491, 2018 04. |
Meta-analysis |
20 Studies (43,341 participants) |
To assess the feasibility of abdominal aortic aneurysm (AAA) screening during transthoracic echocardiography (TTE) and to estimate the prevalence of AAA in patients undergoing TTE. |
Twenty observational cohort studies were identified reporting a total of 43,341 participants (23,291 men and 20,050 women). Hypertension was reported in 41% (95% CI 38-43), hypercholesterolemia in 31% (95% CI 29-32), diabetes mellitus in 20% (95% CI 19-22), and tobacco use in 37% (95% CI 35-38). The aorta was visualised in 86% (95% CI 84-88) of the screened population. The pooled prevalence of AAA in the entire screened population was 0.033 (95% CI 0.024-0.044). The pooled prevalence of AAA in men was 0.046 (95% CI 0.032-0.065) and in women it was 0.014 (95% CI 0.008-0.022). The mean age of participants in whom an AAA was detected ranged across the studies from 66 to 85 years. The mean diameter of the aneurysm identified ranged across the studies from 35 mm to 45 mm. Clinical outcomes in participants with a detected AAA were poorly reported. |
Good |
| 116. Evangelista A, Flachskampf FA, Erbel R, et al. Echocardiography in aortic diseases: EAE recommendations for clinical practice. Eur J Echocardiogr. 11(8):645-58, 2010 Sep. |
Review/Other-Dx |
N/A |
To discuss European Association of Echocardiography (EAE) recommendations for echocardiography in aortic diseases. |
No results stated. |
4 |
| 117. Bieseviciene M, Vaskelyte JJ, Mizariene V, Karaliute R, Lesauskaite V, Verseckaite R. Two-dimensional speckle-tracking echocardiography for evaluation of dilative ascending aorta biomechanics. BMC Cardiovascular Disorders. 17(1):27, 2017 01 13. |
Observational-Dx |
97 Patients |
To study possible interfaces between noninvasive biomechanical and speckle-tracking (ST) echocardiographic data from dilated aortas. |
All linear diameters of the ascending aorta were increased in group 2 (>45 mm diameter) (p < 0.05). LD of the anterior aortic wall (p < 0.05) and TD of both aortic walls (p < 0.001) were least in group 2. VL of the posterior and anterior walls diminished in group 2 (p = 0.01). Aortic strain and distensibility were least (p = 0.028 and p = 0.001, respectively) and elastic modulus and stiffness index ß values were greatest in group 2, although without statistical significance. |
4 |
| 118. American College of Radiology. ACR Appropriateness Criteria® Radiation Dose Assessment Introduction. Available at: https://www.acr.org/-/media/ACR/Files/Appropriateness-Criteria/RadiationDoseAssessmentIntro.pdf. |
Review/Other-Dx |
N/A |
To provide evidence-based guidelines on exposure of patients to ionizing radiation. |
No abstract available. |
4 |
